Park Youngbin, Sung Ki Sub, Kim Ji Hoon, Myung Jinwoo, Hong Ju Young
Department of Emergency Medicine, Yonsei University College of Medicine, Seoul, Korea.
SS-ENG Co., Ltd., Bucheon, Korea.
Clin Exp Emerg Med. 2023 Mar;10(1):44-51. doi: 10.15441/ceem.22.342. Epub 2023 Jan 18.
This study aimed to introduce a novel negative pressure aerosol box (Carrycure Isolator) and to test its efficiency and limitations, with the hope of suggesting improvements and further directions.
A novel aerosol box (Carrycure Isolator) was invented. A single-center, randomized, crossover simulation study of 28 emergency medicine physicians was designed. Three trials of each participant using an intubation manikin were conducted, including intubation without the aerosol box (trial A), intubation with the aerosol box (trial B), and intubation with the aerosol box after familiarization (trial C). The primary endpoint was the time to intubation. The secondary endpoints were first-attempt success, number of attempts, percentage of glottic opening score, and Cormack-Lehane view. Collected data were statistically analyzed for their significance.
The median times to intubation of trials A, B, and C were 30.5 (interquartile range [IQR], 28.0-40.0 seconds), 59.0 (IQR, 50.0-75.5 seconds), and 34.0 seconds (IQR, 30.5-47.0 seconds), respectively. Post hoc analysis showed that the time to intubation in trial B was significantly longer than that in trial A (P<0.05), while that the time to intubation in trial C was significantly shorter than that in trial B (P<0.05).
concerning secondary endpoints showed similar patterns. Participants reported performing intubation with Carrycure Isolator to be relatively difficult, necessitating significant arm movement and view restrictions while increasing their time to intubation.
Physicians took a longer time to intubate a manikin using the Carrycure Isolator, a novel negative pressure aerosol box. However, the time was improved after a period of familiarization.
本研究旨在介绍一种新型负压气溶胶箱（Carrycure隔离器），并测试其效率和局限性，以期提出改进建议和进一步的研究方向。
发明了一种新型气溶胶箱（Carrycure隔离器）。设计了一项针对28名急诊医学医生的单中心、随机、交叉模拟研究。对每位参与者使用插管人体模型进行三项试验，包括不使用气溶胶箱插管（试验A）、使用气溶胶箱插管（试验B）以及熟悉后使用气溶胶箱插管（试验C）。主要终点是插管时间。次要终点包括首次尝试成功率、尝试次数、声门开放评分百分比和Cormack-Lehane喉镜视野分级。对收集的数据进行统计学显著性分析。
试验A、B和C的插管中位时间分别为30.5秒（四分位间距[IQR]，28.0 - 40.0秒）、59.0秒（IQR，50.0 - 75.5秒）和34.0秒（IQR，30.5 - 47.0秒）。事后分析表明，试验B的插管时间显著长于试验A（P<0.05），而试验C的插管时间显著短于试验B（P<0.05）。
关于次要终点也呈现出类似模式。参与者报告称使用Carrycure隔离器进行插管相对困难，需要大幅度移动手臂且视野受限，同时增加了插管时间。
使用新型负压气溶胶箱Carrycure隔离器对人体模型插管时，医生花费的时间更长。然而，经过一段时间的熟悉后时间有所改善。
