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隐睾术后致少弱畸形精子症 1 例:跨性别生育力保存

A Case of Oligoasthenoteratozoospermia Following Genital Tucking: Transgender Fertility Preservation.

机构信息

Leicester Fertility Centre, Assisted Conception Unit, University Hospitals of Leicester NHS Trust, Leicester Royal Infirmary, Leicester, UK.

Department of Health Sciences, University of Leicester, Leicester, UK.

出版信息

Reprod Sci. 2023 Jul;30(7):2248-2251. doi: 10.1007/s43032-023-01168-1. Epub 2023 Jan 18.

DOI:10.1007/s43032-023-01168-1
PMID:36653587
Abstract

Genital tucking is a behavioural practice facilitating gender expression by genitalia concealment. Genital tucking can be achieved by either pushing the testicles into the inguinal canal and/or securing the scrotum and penis between the legs towards the buttocks. Genital tucking has a negative impact on spermatogenesis, and therefore can result in a suboptimal sample and impaired sperm parameters. Fertility cryopreservation is recommended prior to hormone therapy or elective surgery, and therefore, the practice of genital tucking prior to fertility preservation could result in lesser quality and fewer samples being stored for future use. This case study presents a transwoman, aged 20-30, displaying severe oligoasthenoteratozoospermia derived from genital tucking. The case discusses how the cessation of genital tucking resulted in improved semen parameters, and therefore improved the quality and quantity of samples stored for future use. Fundamentally, the case highlights the necessity for health professionals to broaden their understanding and awareness of genital tucking, the impact it has on fertility, and how to better advise patients prior to fertility cryopreservation.

摘要

生殖器内卷是一种通过生殖器隐蔽来促进性别表达的行为实践。生殖器内卷可以通过将睾丸推入腹股沟管,和/或将阴囊和阴茎固定在两腿之间向臀部方向来实现。生殖器内卷会对精子发生产生负面影响,因此可能导致样本质量不佳和精子参数受损。建议在激素治疗或选择性手术前进行生育力冷冻保存,因此,在进行生育力保存之前进行生殖器内卷的做法可能会导致储存的样本质量较差,数量较少。本案例研究介绍了一位年龄在 20-30 岁之间的跨性别女性,其表现出严重的少精症、弱精症和畸形精子症,这是由于生殖器内卷引起的。该案例讨论了停止生殖器内卷如何导致精液参数的改善,从而提高了未来使用的样本的质量和数量。从根本上讲,该案例强调了卫生专业人员有必要扩大对生殖器内卷的理解和认识,了解其对生育能力的影响,以及如何在进行生育力冷冻保存之前更好地为患者提供建议。

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引用本文的文献

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"I was largely unguided trying to figure it out on my own": Experiences of genital tucking among transfeminine and gender diverse individuals.“我在很大程度上是在无人指导的情况下独自摸索着弄清楚的”:跨性别女性和性别多元个体进行生殖器隐匿手术的经历
Int J Transgend Health. 2024 Apr 4;26(3):825-836. doi: 10.1080/26895269.2024.2333533. eCollection 2025.
2
Clinical management of transgender and non-binary patients in the fertility preservation service: Current evidence.生育力保存服务中跨性别和非二元性别人群患者的临床管理:当前证据
Int J Transgend Health. 2023 Nov 24;25(4):663-680. doi: 10.1080/26895269.2023.2284775. eCollection 2024.

本文引用的文献

1
A cohort study on factors impairing semen quality in transgender women.一项关于影响跨性别女性精液质量因素的队列研究。
Am J Obstet Gynecol. 2022 Mar;226(3):390.e1-390.e10. doi: 10.1016/j.ajog.2021.10.020. Epub 2021 Oct 22.
2
Effect of varicoceles on spermatogenesis.精索静脉曲张对精子发生的影响。
Semin Cell Dev Biol. 2022 Jan;121:114-124. doi: 10.1016/j.semcdb.2021.04.005. Epub 2021 May 6.
3
Cryptozoospermia Associated With Genital Tucking Behavior in a Transwoman.一名变性女性中与生殖器内缩行为相关的隐匿精子症。
Rev Urol. 2020;22(4):170-173.
4
Some of the Factors Involved in Male Infertility: A Prospective Review.男性不育的一些相关因素:前瞻性综述
Int J Gen Med. 2020 Feb 5;13:29-41. doi: 10.2147/IJGM.S241099. eCollection 2020.
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Robotic Surgery in Female-To-Male Transition: A Possible Way for Further Improvement.女性向男性转变过程中的机器人手术:进一步改善的一种可能途径。
J Invest Surg. 2021 Jun;34(6):651-652. doi: 10.1080/08941939.2019.1686092. Epub 2019 Dec 3.
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Fertility concerns of the transgender patient.跨性别患者的生育问题。
Transl Androl Urol. 2019 Jun;8(3):209-218. doi: 10.21037/tau.2019.05.09.
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Hormonal and Surgical Treatment Options for Transgender Women and Transfeminine Spectrum Persons.跨性别女性和跨女性谱系人群的激素及手术治疗选择
Psychiatr Clin North Am. 2017 Mar;40(1):99-111. doi: 10.1016/j.psc.2016.10.006. Epub 2016 Dec 22.
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From Tucking to Twisting; A Case of Self-induced Testicular Torsion in a Cross Dressing Male.从掖藏到扭转;一例易装男性自我诱发睾丸扭转的病例
Urol Case Rep. 2016 May 17;7:51-2. doi: 10.1016/j.eucr.2016.04.002. eCollection 2016 Jul.
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Influence of genital heat stress on semen quality in humans.生殖器热应激对人类精液质量的影响。
Andrologia. 2007 Dec;39(6):203-15. doi: 10.1111/j.1439-0272.2007.00794.x.