Agrawal Deepsha, Dhillon Permesh, Siow Isabel, Lee Keng Siang, Spooner Oliver, Yeo Leonard, Bhogal Pervinder
Department of Radiology, Oxford University Hospitals NHS Trust, Oxford, UK.
Department of Interventional Neuroradiology, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Interv Neuroradiol. 2025 Feb;31(1):114-120. doi: 10.1177/15910199231152372. Epub 2023 Jan 18.
The rate of neural circuitry loss in a typical large vessel occlusion well emphasizes that 'Time is Brain'. Every untreated minute in a large vessel ischaemic stroke results in loss of 1.9 million neurons and 13.8 billion synapses. As such, it is essential to optimize the flow-limiting steps in delivering the current standard of care. The current diagnostic model involves recognition of symptoms by patients, followed by access to Emergency Medical Services and subsequent physical examination and neuroimaging in the Emergency Department. With more than 50% of stroke patients using Emergency Medical Services as the first point of care contact, it can be deduced that the outcome of the 'stroke chain of survival' can be improved by addressing the bottleneck of prehospital stroke diagnosis. Here we present a review of the existing technologies.
典型大血管闭塞中神经回路丧失的速率充分强调了“时间就是大脑”。大血管缺血性卒中每未治疗一分钟,就会导致190万个神经元和138亿个突触丧失。因此,优化提供当前标准治疗中的血流限制步骤至关重要。当前的诊断模式包括患者识别症状,随后呼叫紧急医疗服务,以及在急诊科进行后续体格检查和神经影像学检查。超过50%的卒中患者将紧急医疗服务作为首次医疗接触点,可以推断,通过解决院前卒中诊断的瓶颈,可以改善“卒中生存链”的结果。在此,我们对现有技术进行综述。