Akbar Hira F, Kareem Talha, Saleem Nitasha, Seerat Muhammad I, Hussain M Irshad, Javed Irfan, Muhammad Ali Syed
General Surgery, Recep Tayyip Erdogan Hospital, Muzaffargarh, PAK.
General Surgery, Hamad General Hospital, Doha, QAT.
Cureus. 2022 Dec 16;14(12):e32606. doi: 10.7759/cureus.32606. eCollection 2022 Dec.
Background Acute appendicitis remains the most common cause of lower abdominal pain leading to emergency visits. Even though the standard treatment of acute appendicitis remains appendectomy, in recent times, multiple randomized control trials and meta-analyses have deduced conservative treatment as a successful alternative treatment. During the coronavirus disease (COVID) pandemic, with a shortage of staff and resources, treatment with conservative management of uncomplicated acute appendicitis became very beneficial under certain circumstances and conditions. This study aimed to assess whether it is effective to manage patients with uncomplicated acute appendicitis with antibiotic therapy. Methodology This was a single hospital based retrospective, cross-sectional study from Jan 2015 to May 2020. Patients with clinical and radiological features of uncomplicated acute appendicitis with Alvarado's score >6 were included in the study. Patients were kept on antibiotics, intravenous fluids, and analgesia as part of a conservative regime. Those who failed to respond to conservative therapy were managed surgically. The follow-up period was six months. Results One hundred eighty-two cases of uncomplicated acute appendicitis were included and managed conservatively, of which 52.2% were males while 47.8% were females. The median age of the patients was 26 years. Conservative treatment was successful in 26.2% of the patients, with a recurrence of 5.5% in the six-month follow-up period. The mean number of days of hospital stay was three days in patients treated with conservative or surgical treatment. Conclusion Conservative management is gaining popularity, and many centers are inclined towards non-operative management; however, appendectomy remains the gold standard treatment for appendicitis.
背景 急性阑尾炎仍然是导致急诊就诊的最常见下腹痛原因。尽管急性阑尾炎的标准治疗方法仍是阑尾切除术,但近年来,多项随机对照试验和荟萃分析已推断保守治疗是一种成功的替代治疗方法。在冠状病毒病(COVID)大流行期间,由于人员和资源短缺,在某些情况和条件下,对单纯性急性阑尾炎进行保守治疗变得非常有益。本研究旨在评估用抗生素治疗单纯性急性阑尾炎患者是否有效。方法 这是一项基于单一医院的回顾性横断面研究,时间跨度为2015年1月至2020年5月。纳入研究的患者具有单纯性急性阑尾炎的临床和放射学特征,且阿尔瓦拉多评分>6。作为保守治疗方案的一部分,患者接受抗生素、静脉输液和镇痛治疗。对保守治疗无反应的患者则进行手术治疗。随访期为六个月。结果 共纳入182例单纯性急性阑尾炎患者并进行保守治疗,其中男性占52.2%,女性占47.8%。患者的中位年龄为26岁。26.2%的患者保守治疗成功,在六个月的随访期内复发率为5.5%。接受保守治疗或手术治疗的患者平均住院天数均为三天。结论 保守治疗越来越受欢迎,许多中心倾向于非手术治疗;然而,阑尾切除术仍然是阑尾炎的金标准治疗方法。