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表现为急性阑尾炎的阑尾类癌肿瘤。

Carcinoid tumors of appendix presenting as acute appendicitis.

作者信息

Barut Bora, Gönültaş Fatih

机构信息

Department of General Surgery, İnönü University Faculty of Medicine, Malatya-Turkey.

出版信息

Ulus Travma Acil Cerrahi Derg. 2019 Sep;25(5):510-513. doi: 10.5505/tjtes.2018.99569.

Abstract

BACKGROUND

We aim to present the data of patients who underwent appendectomy due to acute appendicitis, and incidental carcinoid tumor was detected on pathology.

METHODS

Retrospective analysis of the patient charts between January 1999 and September 2018 were performed.

RESULTS

2778 appendectomy was performed due to acute appendicitis. Appendiceal carcinoid tumor was detected in 12 (0.43%) patients. Eight patients were (66.7%) female. Median age 37.5 years (range: 21-60). The median tumor size was 0.7 cm (range: 0.1-2.5). No perforation was detected. Eleven patients underwent appendectomy, and one patient had right hemicolectomy. The median follow-up period was 41.5 months (range: 22-49). There were no recurrences.

CONCLUSION

Appendix carcinoid tumors are quite rare, usually asymptomatic and diagnosed incidentally on histopathological examination after appendectomy. The treatment of carcinoid tumors of the appendix is directly related to the tumor size, localization, presence of lymphovascular and mesoappendix invasion, mitotic activation rate and level of Ki67. Thus, it is important to follow the histopathological results after appendectomy. The prognosis of appendix carcinoid tumors is very good if the appendix is non-perforated.

摘要

背景

我们旨在呈现因急性阑尾炎接受阑尾切除术且病理检查发现意外类癌肿瘤的患者数据。

方法

对1999年1月至2018年9月期间的患者病历进行回顾性分析。

结果

因急性阑尾炎进行了2778例阑尾切除术。在12例(0.43%)患者中检测到阑尾类癌肿瘤。8例患者(66.7%)为女性。中位年龄37.5岁(范围:21 - 60岁)。肿瘤中位大小为0.7厘米(范围:0.1 - 2.5厘米)。未检测到穿孔。11例患者接受了阑尾切除术,1例患者进行了右半结肠切除术。中位随访期为41.5个月(范围:22 - 49个月)。无复发情况。

结论

阑尾类癌肿瘤相当罕见,通常无症状,在阑尾切除术后经组织病理学检查偶然诊断。阑尾类癌肿瘤的治疗与肿瘤大小、定位、是否存在淋巴管和阑尾系膜侵犯、有丝分裂激活率以及Ki67水平直接相关。因此,阑尾切除术后关注组织病理学结果很重要。如果阑尾未穿孔,阑尾类癌肿瘤的预后非常好。

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