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炎症性疾病的新靶点:番茄红素。

A New Target in Inflammatory Diseases: Lycopene.

作者信息

Karaköy Zeynep, Cadirci Elif, Dincer Busra

机构信息

Department of Pharmacology, Erzincan Binali Yildirim University, Faculty of Pharmacy, Erzincan, Turkey.

Department of Pharmacology, Ataturk University, Faculty of Medicine, Erzurum, Turkey.

出版信息

Eurasian J Med. 2022 Dec;54(Suppl1):23-28. doi: 10.5152/eurasianjmed.2022.22303.

Abstract

Inflammation is a response to various injuries, illnesses, and severe trauma. The primary function of inflammation is to combat pathogens, eliminate them from the body, and initiate wound healing. However, inflammation also contributes to numerous diseases, such as cancer, cardiovascular disease, diabetes, obesity, osteoporosis, rheumatoid arthritis, inflammatory bowel disease, and asthma. As the importance of nutrition in maintaining human health has become increasingly recognized, the consumption of natural antioxidants has gained popularity, especially in developed countries. A growing body of research has shown that consuming foods rich in lycopene can protect individuals from a range of conditions, including cancer, heart disease, and other diseases. As a result, lycopene is gaining recognition as a potential protective antioxidant in the fields of medicine and pharmacology. This review aims to highlight the effects of lycopene on inflammatory diseases and provide a foundational understanding for researchers interested in further research on lycopene.

摘要

炎症是对各种损伤、疾病和严重创伤的一种反应。炎症的主要功能是对抗病原体,将其从体内清除,并启动伤口愈合。然而,炎症也会引发多种疾病,如癌症、心血管疾病、糖尿病、肥胖症、骨质疏松症、类风湿性关节炎、炎症性肠病和哮喘。随着营养在维持人类健康中的重要性日益得到认可,天然抗氧化剂的消费越来越普遍,尤其是在发达国家。越来越多的研究表明,食用富含番茄红素的食物可以保护个体免受一系列疾病的侵害,包括癌症、心脏病和其他疾病。因此,番茄红素在医学和药理学领域正逐渐被视为一种潜在的保护性抗氧化剂。本综述旨在强调番茄红素对炎症性疾病的影响,并为有兴趣进一步研究番茄红素的研究人员提供基础认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7230/11163352/578e04771620/eajm-54-S1-S23_f001.jpg

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