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性传播感染门诊中 18 至 26 岁性活跃的年轻人中人类乳头瘤病毒疫苗接种率。

Human papillomavirus vaccination coverage among sexually active young adults aged 18 to 26 at a sexually transmitted infections clinic.

机构信息

Department of Medicine, 6752Brown University, Providence, RI, USA.

Department of Behavioral and Social Sciences, 12321Brown University School of Public Health, Providence, RI, USA.

出版信息

Int J STD AIDS. 2023 Apr;34(5):315-321. doi: 10.1177/09564624221146605. Epub 2023 Jan 19.

DOI:10.1177/09564624221146605
PMID:36655673
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10073331/
Abstract

BACKGROUND

Human papillomavirus (HPV) vaccination is the most effective biomedical intervention for HPV infections. HPV vaccination rate among sexually active young adults is largely unknown.

METHODS

Patients aged 18-26 years, who attended the Rhode Island Sexually Transmitted Infections Clinic between 2013-2018, were included in the study. We extracted demographics, behavioral characteristics, and HPV vaccination status from electronic medical records. Exploratory logistic regressions were conducted to identify factors associated with vaccination status.

RESULTS

Among 2729 eligible individuals, the median age was 23 years (interquartile range: 22-25). Only 8.1% of males and 24.8% of females received at least one dose of HPV vaccine. Females were 144% (crude odds ratio [cOR]: 2.44, 95% confidence interval [CI]: 2.03, 2.94) more likely to receive at least one dose of HPV vaccine than males. Being Black/African American (B/AA) or Hispanic/Latino (H/L) was associated with a 21% (cOR: 0.79, 95% CI: 0.62, 1.00) and 34% (cOR: 0.66, 95% CI: 0.53, 0.81) decrease in the odds of vaccination, respectively.

CONCLUSIONS

HPV vaccination rate was low among sexually active young adults. Gender and racial/ethnic disparities existed in HPV vaccination. Interventions are needed to promote HPV vaccination among sexually active young adults, especially B/AA and H/L communities.

摘要

背景

人乳头瘤病毒(HPV)疫苗接种是针对 HPV 感染最有效的生物医学干预措施。性行为活跃的年轻成年人 HPV 疫苗接种率在很大程度上尚不清楚。

方法

本研究纳入了 2013 年至 2018 年间在罗德岛性传播感染诊所就诊的年龄在 18-26 岁的患者。我们从电子病历中提取人口统计学、行为特征和 HPV 疫苗接种状况。采用探索性逻辑回归分析确定与接种状况相关的因素。

结果

在 2729 名符合条件的个体中,中位年龄为 23 岁(四分位距:22-25 岁)。仅有 8.1%的男性和 24.8%的女性至少接种了一剂 HPV 疫苗。女性接种至少一剂 HPV 疫苗的可能性是男性的 144%(粗优势比[cOR]:2.44,95%置信区间[CI]:2.03,2.94)。非裔美国人(B/AA)或西班牙裔/拉丁裔(H/L)与接种 HPV 疫苗的可能性降低 21%(cOR:0.79,95%CI:0.62,1.00)和 34%(cOR:0.66,95%CI:0.53,0.81)相关。

结论

性行为活跃的年轻成年人 HPV 疫苗接种率较低。HPV 疫苗接种在性别和种族/族裔方面存在差异。需要采取干预措施,促进性行为活跃的年轻成年人接种 HPV 疫苗,尤其是 B/AA 和 H/L 社区。

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