Hori Yuki, Nagano Akihito, Miyazaki Tatsuhiko, Kato Hiroki, Tsugita Masanori, Nishimoto Yutaka, Akiyama Haruhiko
The Department of Orthopaedic Surgery, Gifu University School of Medicine, Gifu, Japan.
The Department of Pathology, Gifu University School of Medicine, Gifu, Japan.
JBJS Case Connect. 2023 Jan 19;13(1). doi: 10.2106/JBJS.CC.22.00520. eCollection 2023 Jan 1.
A 76-year-old woman presented with a 2-month history of right shoulder pain with no apparent cause. Radiography revealed an ill-defined osteolytic lesion in the right scapular spine with a pathological fracture. Malignant bone tumor was suspected, and a biopsy was performed. Pathological examination with gold hydroxamic acid staining revealed phosphoglyceride crystal deposition. Lesion curettage was performed, and her symptoms improved. No recurrence was observed at the 3-year postoperative follow-up.
Phosphoglyceride crystal deposition in the bone is an extremely rare disease. The gold hydroxamic acid staining method might be useful for the diagnosis of this condition.
一名76岁女性出现右肩疼痛2个月，无明显诱因。影像学检查显示右肩胛冈有边界不清的溶骨性病变，并伴有病理性骨折。怀疑为恶性骨肿瘤，遂进行活检。用金异羟肟酸染色进行病理检查发现磷酸甘油酯晶体沉积。进行了病灶刮除术，患者症状改善。术后3年随访未观察到复发。
骨中磷酸甘油酯晶体沉积是一种极其罕见的疾病。金异羟肟酸染色法可能有助于诊断这种疾病。
