GenesisCare, Fort Myers, Florida.
Department of Radiation Medicine and Applied Sciences, University of California, San Diego, La Jolla, California.
Int J Radiat Oncol Biol Phys. 2023 Jul 15;116(4):729-735. doi: 10.1016/j.ijrobp.2023.01.005. Epub 2023 Jan 17.
Outpatient care for patients with cancer compromises 60% to 70% of health care costs during the last 6 months of life. Recent approvals for expensive biologics and growing support for lower-cost hypofractionated radiation therapy in the palliative management of advanced cancer have introduced offsetting spending effects on end-of-life care that may shift overall expenditures for this patient cohort.
In this descriptive retrospective cohort study, end-of-life care is defined as the aggregate of medical services and supplies, including drugs, furnished to patients with cancer in the outpatient setting during the last 6 months of life. A total of 84,744 Medicare beneficiaries with a cancer diagnosis were identified as having died between January 1, 2016, and December 31, 2019. Beneficiaries with Medicare Advantage were not included in this study. Medicare Standard Analytical Files were abstracted for all paid claims for these beneficiaries during the last 6 months of life, and provider payments were summed according to service or supply category and year of death. Comparisons of service and supply utilization and costs between patient groups were performed using the Pearson χ test.
The average total Medicare Part B payments per treated beneficiary during the last 6 month of life increased by 12.0% between 2016 and 2019 (from $14,487 to $16,227), with the greatest absolute cost increase observed for the medical oncology category (from $7030 to $9436 [+34.2%]). Within the medical oncology category, drug utilization shifted away from less costly chemotherapy and hormone therapy agents and toward more expensive immunotherapy agents. The increase in immunotherapy utilization and drug costs alone accounted for 84% of the increase in total Part B payments for all categories during the period.
Although costs related to end-of-life care for nearly all cost categories have remained relatively stable, oncology drug costs overall and immunotherapy costs specifically have accelerated and account almost entirely for the observed overall increase in outpatient cost burden for Medicare.
在生命的最后 6 个月,癌症患者的门诊护理占医疗保健费用的 60%至 70%。最近昂贵的生物制剂获得批准,并在晚期癌症的姑息治疗中越来越支持低成本的低分割放射治疗,这对临终护理产生了抵消性的支出影响,可能会改变这一患者群体的总体支出。
在这项描述性回顾性队列研究中,临终护理被定义为在生命的最后 6 个月中,为门诊环境中的癌症患者提供的医疗服务和用品的总和,包括药物。共确定了 84744 名患有癌症的 Medicare 受益人,他们在 2016 年 1 月 1 日至 2019 年 12 月 31 日期间死亡。本研究不包括参加 Medicare Advantage 的受益人。从这些受益人的最后 6 个月的所有已付索赔中提取 Medicare 标准分析文件,并按服务或供应类别和死亡年份对提供者付款进行汇总。使用 Pearson χ 检验比较患者组之间的服务和供应利用情况和成本。
在生命的最后 6 个月中,每位接受治疗的受益人的平均 Medicare Part B 总支付额从 2016 年到 2019 年增加了 12.0%(从 14487 美元增加到 16227 美元),其中医疗肿瘤学类别(从 7030 美元增加到 9436 美元[增加 34.2%])的绝对成本增加最大。在医疗肿瘤学类别中,药物利用从成本较低的化疗和激素治疗药物转向更昂贵的免疫治疗药物。仅免疫治疗利用率和药物成本的增加就占该期间所有类别 Part B 总支付额增加的 84%。
尽管几乎所有成本类别的临终护理相关成本相对稳定,但肿瘤药物成本总体上和免疫治疗成本具体上都在加速,几乎完全解释了 Medicare 门诊成本负担观察到的总体增加。