• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

基于证据的胃食管交界部癌手术方法:我们如何进行机器人经裂孔下纵隔解剖和食管空肠吻合术。

Evidence-Based Surgical Approach to Gastroesophageal Junction Cancer: How We Do Robotic Transhiatal Lower Mediastinal Dissection and Esophagojejunostomy.

作者信息

Hirata Yuki, Mansfield Paul, Badgwell Brian D, Ikoma Naruhiko

机构信息

Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

出版信息

Ann Surg Oncol. 2023 May;30(5):2956. doi: 10.1245/s10434-022-13057-z. Epub 2023 Jan 19.

DOI:10.1245/s10434-022-13057-z
PMID:36658247
Abstract

Currently available data suggest that gastroesophageal junction (GEJ) cancers with an esophageal extension less than 2 cm can be removed using gastrectomy with a limited esophagectomy via a transhiatal approach and selective lower mediastinal dissection. In this multimedia article, we demonstrate our approach to robotic total gastrectomy with data-driven mediastinal lymph node (LN) dissection and sutured esophagojejunostomy for GEJ cancer.The video shows the case of a 63-year-old man with Siewert type 2 GEJ adenocarcinoma. The size of the tumor was 3 cm, and its esophageal extension was 2 cm. The man underwent preoperative chemoradiotherapy (5-FU/oxaliplatin, 45 Gy) with excellent treatment effect. After dissection of the esophagus from the bilateral diaphragmatic crus, surrounding lymph node (LN) tissue (#110) was identified and dissected. In this case, intraoperative findings showed the posterior lower mediastinal LNs (#112) to be swollen, and they were sampled. Surgeons should take care to avoid penetration of the pleura and thoracic duct injury if pleura penetration is oncologically unnecessary. Because the esophagus often is thickened and prone to ischemia after preoperative chemoradiotherapy, the authors perform the anastomosis with hand-suturing techniques regardless whether a robotic or open approach is used. The patient recovered well and was discharged on postoperative day 4 in good condition. Pathology reported a ypT1bN0 tumor with negative margins.

摘要

目前可得的数据表明,食管延伸小于2 cm的胃食管交界(GEJ)癌可通过经裂孔途径行胃切除术并有限食管切除术及选择性下纵隔清扫术来切除。在这篇多媒体文章中,我们展示了我们采用数据驱动的纵隔淋巴结(LN)清扫及缝合式食管空肠吻合术治疗GEJ癌的机器人全胃切除术方法。视频展示了一名63岁患有Siewert 2型GEJ腺癌男性患者的病例。肿瘤大小为3 cm,食管延伸为2 cm。该男性患者接受了术前放化疗(5-氟尿嘧啶/奥沙利铂,45 Gy),治疗效果良好。从双侧膈脚游离食管后,识别并清扫了周围淋巴结(LN)组织(#110)。在该病例中,术中发现后下纵隔淋巴结(#112)肿大,并进行了取样。如果从肿瘤学角度不需要穿透胸膜,外科医生应注意避免穿透胸膜及胸导管损伤。由于术前放化疗后食管常增厚且易发生缺血,无论采用机器人手术还是开放手术,作者均采用手工缝合技术进行吻合。患者恢复良好,术后第4天状况良好出院。病理报告为ypT1bN0肿瘤,切缘阴性。

相似文献

1
Evidence-Based Surgical Approach to Gastroesophageal Junction Cancer: How We Do Robotic Transhiatal Lower Mediastinal Dissection and Esophagojejunostomy.基于证据的胃食管交界部癌手术方法:我们如何进行机器人经裂孔下纵隔解剖和食管空肠吻合术。
Ann Surg Oncol. 2023 May;30(5):2956. doi: 10.1245/s10434-022-13057-z. Epub 2023 Jan 19.
2
Laparoscopic en bloc lower mediastinal lymph node dissection via transhiatal approach for adenocarcinoma of esophagogastric junction.经食管裂孔入路腹腔镜整块中下纵隔淋巴结清扫术治疗食管胃结合部腺癌
Surg Oncol. 2021 Mar;36:34-35. doi: 10.1016/j.suronc.2020.11.010. Epub 2020 Nov 21.
3
[Effects of robotic and laparoscopic-assisted surgery on lymph node dissection and short-term outcomes in patients with Siewert II adenocarcinoma of esophagogastric junction].[机器人手术与腹腔镜辅助手术对食管胃交界部Siewert II型腺癌患者淋巴结清扫及短期预后的影响]
Zhonghua Wei Chang Wai Ke Za Zhi. 2019 Feb 25;22(2):156-163.
4
Worldwide trends in surgical techniques in the treatment of esophageal and gastroesophageal junction cancer.全球食管和胃食管交界癌治疗中手术技术的趋势
Dis Esophagus. 2017 Jan 1;30(1):1-7. doi: 10.1111/dote.12480.
5
[Survival comparison of Siewert II adenocarcinoma of esophagogastric junction between transthoracic and transabdominal approaches:a joint data analysis of thoracic and gastrointestinal surgery].[经胸与经腹入路治疗食管胃交界部Siewert II型腺癌的生存比较:胸外科与胃肠外科联合数据分析]
Zhonghua Wei Chang Wai Ke Za Zhi. 2019 Feb 25;22(2):132-142.
6
The CARDIA-trial protocol: a multinational, prospective, randomized, clinical trial comparing transthoracic esophagectomy with transhiatal extended gastrectomy in adenocarcinoma of the gastroesophageal junction (GEJ) type II.CARDIA 试验方案:一项比较经胸食管切除术与经胸食管裂孔扩大胃切除术治疗 II 型胃食管结合部腺癌的多中心、前瞻性、随机、临床试验。
BMC Cancer. 2020 Aug 20;20(1):781. doi: 10.1186/s12885-020-07152-1.
7
Surgical approach to advanced Siewert II cancer: beyond the borders? The West Side.晚期Siewert II型癌的手术入路:超越边界?西区。
Updates Surg. 2023 Feb;75(2):329-333. doi: 10.1007/s13304-022-01363-w. Epub 2022 Aug 24.
8
Proximal margin length with transhiatal gastrectomy for Siewert type II and III adenocarcinomas of the oesophagogastric junction.食管胃交界部 Siewert Ⅱ型和Ⅲ型腺癌经食管裂孔胃切除术的近端切缘长度。
Br J Surg. 2013 Jul;100(8):1050-4. doi: 10.1002/bjs.9170.
9
Combined total gastrectomy, total esophagectomy, and D2 lymph node dissection with transverse colonic interposition for adenocarcinoma of the gastroesophageal junction.胃食管结合部腺癌行全胃切除、全食管切除、D2 淋巴结清扫加横结肠间置术。
Surg Today. 2011 Sep;41(9):1319-23. doi: 10.1007/s00595-010-4412-z. Epub 2011 Aug 26.
10
[Comparison of the effect of lymph node dissection performed by Ivor-Lewis or left-sided thoracic esophagogastrectomy for Siewert type Ⅱ adenocarcinoma of the esophagogastric junction].[Ivor-Lewis手术或左侧开胸食管胃切除术行淋巴结清扫对食管胃交界部SiewertⅡ型腺癌的疗效比较]
Zhonghua Zhong Liu Za Zhi. 2017 Mar 23;39(3):190-194. doi: 10.3760/cma.j.issn.0253-3766.2017.03.006.

引用本文的文献

1
Modified Proximal Gastrectomy and D2 Lymphadenectomy Is an Oncologically Sound Operation for Locally Advanced Proximal and GEJ Adenocarcinoma.改良近端胃切除术及D2淋巴结清扫术是治疗局部进展期近端及胃食管交界腺癌的肿瘤学合理术式。
Cancers (Basel). 2025 Jul 24;17(15):2455. doi: 10.3390/cancers17152455.

本文引用的文献

1
Mapping of Lymph Node Metastasis From Esophagogastric Junction Tumors: A Prospective Nationwide Multicenter Study.胃食管结合部肿瘤淋巴结转移的定位:一项全国前瞻性多中心研究。
Ann Surg. 2021 Jul 1;274(1):120-127. doi: 10.1097/SLA.0000000000003499.
2
Phase II trial of preoperative chemoradiation in patients with localized gastric adenocarcinoma (RTOG 9904): quality of combined modality therapy and pathologic response.局限性胃腺癌患者术前放化疗的II期试验(RTOG 9904):综合治疗模式的质量和病理反应
J Clin Oncol. 2006 Aug 20;24(24):3953-8. doi: 10.1200/JCO.2006.06.4840.