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胃食管结合部腺癌行全胃切除、全食管切除、D2 淋巴结清扫加横结肠间置术。

Combined total gastrectomy, total esophagectomy, and D2 lymph node dissection with transverse colonic interposition for adenocarcinoma of the gastroesophageal junction.

机构信息

Department of Gastrointestinal Surgery, Instituto Oncológico Fundación Arturo López Pérez, Rancagua 878, Santiago, Chile.

出版信息

Surg Today. 2011 Sep;41(9):1319-23. doi: 10.1007/s00595-010-4412-z. Epub 2011 Aug 26.

DOI:10.1007/s00595-010-4412-z
PMID:21874440
Abstract

The surgical treatment of adenocarcinoma of the gastroesophageal junction (GEJ) is complex. A large tumor involving a substantial portion of both the esophagus and stomach requires complete resection with negative proximal and distal margins as well as D2 lymph node dissection. Some investigators have found that patients who do not undergo radical resection have a worse prognosis; however, more aggressive surgical treatments are associated with increased morbidity and mortality. We describe our operative technique designed for complete resection of tumors of the GEJ. We used this technique to operate on nine patients, none of whom suffered anastomotic leakage or necrosis of the colonic interposition graft.

摘要

胃食管结合部腺癌(GEJ)的外科治疗较为复杂。对于累及食管和胃大部的巨大肿瘤,需要行整块切除,近端和远端切缘阴性,并清扫 D2 淋巴结。一些研究人员发现,未行根治性切除术的患者预后较差;然而,更激进的手术治疗与更高的发病率和死亡率相关。我们描述了一种用于完全切除 GEJ 肿瘤的手术技术。我们使用该技术对 9 例患者进行了手术,无一例发生吻合口漏或结肠间置移植的坏死。

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本文引用的文献

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Optimal dose of preoperative enteral immunonutrition for patients with esophageal cancer.食管癌患者术前肠内免疫营养的最佳剂量。
Surg Today. 2009;39(10):855-60. doi: 10.1007/s00595-009-3967-z. Epub 2009 Sep 27.
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Multidisciplinary management of gastric and gastroesophageal cancers.胃癌和胃食管癌的多学科管理
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Adenocarcinoma of the gastroesophageal junction: influence of esophageal resection margin and operative approach on outcome.胃食管交界腺癌:食管切缘及手术方式对预后的影响
Proximal gastrectomy with jejunal interposition and TGRY anastomosis for proximal gastric cancer.
近端胃癌的近端胃切除术加空肠间置及TGRY吻合术
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Two-stage operation for synchronous triple primary cancer of the esophagus, stomach, and ampulla of Vater: report of a case.食管、胃和壶腹同步三原发癌的两阶段手术:1例报告
Surg Today. 2014 May;44(5):967-71. doi: 10.1007/s00595-013-0549-x. Epub 2013 Mar 17.
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Adenocarcinoma of the esophagus and cardia: a review of the disease and its treatment.食管和贲门腺癌:疾病及其治疗综述
Ann Surg Oncol. 2006 Jan;13(1):12-30. doi: 10.1245/ASO.2005.12.025. Epub 2006 Jan 1.
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Adenocarcinoma of the gastric cardia: what is the optimal surgical approach?贲门腺癌:最佳手术方式是什么?
J Am Coll Surg. 2004 Dec;199(6):880-6. doi: 10.1016/j.jamcollsurg.2004.08.015.
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Mortality and morbidity in gastro-oesophageal cancer surgery: initial results of ASCOT multicentre prospective cohort study.胃食管癌手术的死亡率和发病率:ASCOT多中心前瞻性队列研究的初步结果。
BMJ. 2003 Nov 22;327(7425):1192-7. doi: 10.1136/bmj.327.7425.1192.
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