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单纯二尖瓣反流行二尖瓣成形术后的早期结果。

Early results after mitral valvuloplasty for pure mitral regurgitation.

作者信息

Gallino A, Jenni R, Hurni R, Hirzel H O, Krayenbühl H P, Egloff L, Rothlin M, Schönbeck M, Turina M

机构信息

Department of Medicine, University Hospital, Zürich, Switzerland.

出版信息

Eur Heart J. 1987 Aug;8(8):902-5. doi: 10.1093/oxfordjournals.eurheartj.a062355.

DOI:10.1093/oxfordjournals.eurheartj.a062355
PMID:3665947
Abstract

In this study we present the results of 105 consecutive patients with pure mitral regurgitation who underwent surgical treatment. In all patients mitral regurgitation was associated with mitral valve prolapse: 54 patients underwent mitral valvuloplasty and 51 patients mitral valve replacement. Clinical assessment and echocardiography were used as follow-up criteria at one year after surgery. After mitral valvuloplasty, NYHA decreased from 2.7 +/- 0.8 to 1.1 +/- 0.7 (P less than 0.01) and workload capacity increased from 65 +/- 28% to 96 +/- 25% (P less than 0.001); left endsystolic atrial dimension and enddiastolic dimension decreased from 6.2 +/- 0.8 to 4.8 +/- 1.2 cm (P less than 0.001) and from 7.2 +/- 1.3 to 5.9 +/- 0.8 cm (P less than 0.01); ventricular contraction fraction did not change significantly. After mitral valve replacement, clinical and echocardiographic improvement was significant but less remarkable than after valvuloplasty; ventricular contraction fraction fell from 39 +/- 7% to 29 +/- 8% in contrast to patients undergoing mitral valvuloplasty in whom no significant change occurred. Complications were rare in both groups though only a minority of patients undergoing mitral valvuloplasty received anticoagulants. We conclude that mitral valvuloplasty in patients with pure mitral regurgitation when compared with the patients after mitral valve replacement.

摘要

在本研究中,我们呈现了105例接受手术治疗的单纯二尖瓣反流患者的结果。所有患者的二尖瓣反流均与二尖瓣脱垂相关:54例患者接受了二尖瓣成形术,51例患者接受了二尖瓣置换术。术后一年,采用临床评估和超声心动图作为随访标准。二尖瓣成形术后,纽约心脏协会(NYHA)分级从2.7±0.8降至1.1±0.7(P<0.01),工作量能力从65±28%增至96±25%(P<0.001);左心房收缩末期内径和舒张末期内径分别从6.2±0.8降至4.8±1.2 cm(P<0.001)和从7.2±1.3降至5.9±0.8 cm(P<0.01);心室收缩分数无显著变化。二尖瓣置换术后,临床和超声心动图改善显著,但不如二尖瓣成形术后明显;与二尖瓣成形术患者心室收缩分数无显著变化相反,二尖瓣置换术患者的心室收缩分数从39±7%降至29±8%。两组并发症均少见,尽管只有少数接受二尖瓣成形术的患者接受了抗凝治疗。我们得出结论,与二尖瓣置换术后患者相比,单纯二尖瓣反流患者行二尖瓣成形术……(原文最后似乎不完整)

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