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外阴滑膜肉瘤:一例报告及文献复习并讨论保留生育功能的方法

Synovial sarcoma of the vulva: A case report and literature review with discussion on fertility sparing approaches.

作者信息

Schoettle Gabriella, Gulstene Stephanie, Vickress Jason, Sugimoto Akira, D'Souza David

机构信息

Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.

Division of Radiation Oncology, Department of Oncology, London Health Sciences Centre, London, Ontario, Canada.

出版信息

Gynecol Oncol Rep. 2023 Jan 8;45:101132. doi: 10.1016/j.gore.2023.101132. eCollection 2023 Feb.

Abstract

•Vulvar synovial sarcoma is a rare malignancy with unclear treatment guidelines but usually includes surgical resection.•Our literature review demonstrates additional survival benefit from addition of radiotherapy to surgical resection.•There is no specific guidance in the literature for the addition of systemic agents to treat vulvovaginal disease.•Our patient received wide surgical excision and IMRT radiotherapy with no signs of recurrence 2 years from treatment.•She conceived after treatment. This has only been documented once before with different, less accessible treatments.

摘要

•外阴滑膜肉瘤是一种罕见的恶性肿瘤,治疗指南尚不明确,但通常包括手术切除。

•我们的文献综述表明,手术切除加放疗可带来额外的生存获益。

•文献中没有关于添加全身治疗药物来治疗外阴阴道疾病的具体指导。

•我们的患者接受了广泛手术切除和调强适形放疗,治疗后2年无复发迹象。

•她在治疗后怀孕了。此前仅有一次关于不同且较难获得的治疗方法后怀孕的记录。

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