Suppr超能文献

[抗惊厥药与镇静剂联合使用时对镇静剂精神活性的影响(实验研究)]

[Effect of anticonvulsants on the psychotropic activity of tranquilizers in their joint use in an experiment].

作者信息

Zalesov V S, Kolla V E, Khvolis E A

出版信息

Farmakol Toksikol. 1987 Jul-Aug;50(4):15-8.

PMID:3666110
Abstract

Effects of anticonvulsants (phenobarbital, hexamidine, benzonal, difenin, chloracon, trimetin, carbamazepine) on the psychotropic activity of tranquillizers (diazepam, chlordiazepoxide, meprotan, trioxazine, mebicar) were studied in experiments on mice and rats. Thirteen combinations were studied by using corazol test, "open field" and elementary-defensive conditioned response technique. According to all three tests the psychotropic activity was enhanced to the greatest degree by administration of hexamidine in combination with chlordiazepoxide.

摘要

在小鼠和大鼠实验中,研究了抗惊厥药(苯巴比妥、己脒定、苯佐那尔、二苯乙内酰脲、氯拉克酮、三甲双酮、卡马西平)对镇静剂(地西泮、氯氮卓、美普他酮、三氧二氮、美比卡)精神活性的影响。通过使用戊四氮试验、“旷场”试验和基本防御条件反应技术,对13种组合进行了研究。根据所有这三项试验,己脒定与氯氮卓联合给药时,精神活性增强的程度最大。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验