Clinical Medical College, Ningxia Medical University, Yinchuan, China.
Lanzhou University Second Hospital, Lanzhou, China.
BMC Infect Dis. 2023 Jan 20;23(1):35. doi: 10.1186/s12879-023-07985-8.
Escherichia fergusonii is a rare opportunistic pathogen in humans and animals, especially with biofilm.
In one case, E. fergusonii with biofilm was detected in the bile, and silver staining was used to prove it had biofilm. The clinical characteristics and drug susceptibility of eight cases of E. fergusonii retrieved from the literature were also summarized.
This is a case of E. fergusonii with biofilm, which has not been reported in China. The 8 cases retrieved from the literature did not specify whether they had biofilm, but we analyzed their clinical characteristics and drug susceptibility. All patients were treated with antimicrobial drugs. 8 cases showed sensitivity to piperacillin/tazobactam and imipenem in 6 cases (75%), but poor sensitivity to levofloxacin and ciprofloxacin.
The silver staining method proved biofilm in this case, which is the first case of E. fergusonii with biofilm in China.
弗格森埃希氏菌是人类和动物中一种罕见的机会致病菌，特别是会形成生物膜。
在一个案例中，从胆汁中检测到具有生物膜的弗格森埃希氏菌，并使用银染来证明其具有生物膜。还总结了从文献中检索到的 8 例弗格森埃希氏菌的临床特征和药敏性。
这是一例具有生物膜的弗格森埃希氏菌，在中国尚未有报道。从文献中检索到的 8 例并未具体说明是否具有生物膜，但我们分析了它们的临床特征和药敏性。所有患者均接受了抗菌药物治疗。8 例中有 6 例（75%）对哌拉西林/他唑巴坦和亚胺培南敏感，但对左氧氟沙星和环丙沙星的敏感性较差。
银染法证明了该病例中存在生物膜，这是中国首例具有生物膜的弗格森埃希氏菌。
