Morávek P
Department of Urology, Charles University Medical School, Hradec Králové, Czechoslovakia.
Int Urol Nephrol. 1987;19(3):315-9. doi: 10.1007/BF02549869.
Precise determination of the extent of lymph node involvement is of decisive importance for therapy of prostatic cancer. For this reason staging pelvic lymphadenectomy is fully indicated. Some authors expect from pelvic lymphadenectomy a therapeutic effect, too. The procedure is performed as a part of radical prostatectomy or before radiation therapy. In the period 1978 to 1984 the authors followed two groups of patients treated with external radiotherapy using betatron Brown-Boveri. Group A--irradiation only, Group B--irradiation after previous en bloc pelvic lymphadenectomy. The total number of 0-7-year survival was 56% in Group A and 76% in Group B. In Group B no difference was found in survival of patients with negative or positive nodes. In Group A--with an error in determining N category of lymphography--the survival of patients with negative nodes was significantly higher. Five-year survival was 46% in Group A and 65% in Group B.
准确确定淋巴结受累程度对前列腺癌的治疗具有决定性意义。因此，分期盆腔淋巴结清扫术是完全必要的。一些作者也期望盆腔淋巴结清扫术能产生治疗效果。该手术作为根治性前列腺切除术的一部分或在放疗前进行。1978年至1984年期间，作者对两组接受西门子电子感应加速器外部放疗的患者进行了随访。A组——仅放疗，B组——先行整块盆腔淋巴结清扫术后放疗。0至7年总生存率A组为56%，B组为76%。B组中，淋巴结阴性或阳性患者的生存率无差异。A组——在淋巴造影确定N分期存在误差——淋巴结阴性患者的生存率显著更高。A组5年生存率为46%，B组为65%。
