Kelly L U, Moravek P, Schubert J, Wehnert J
Int Urol Nephrol. 1986;18(1):75-84. doi: 10.1007/BF02082652.
A total of 181 prostatic cancer patients under radiation monotherapy was tested for the therapeutic effect of pelvic lymphadenectomy (PLA). Sixty-seven belonging to the pN0 category formed a highly selective group and presented an 89% rate of 7-year survival. Localized radiation therapy with pelvic irradiation (81 patients) upon conventional exclusion of lymphogenic macro metastases, in probable presence of micrometastases, produced equally good results. Extended pelvic irradiation in cases of conventionally verified regional lymphogenic macrometastases remained without therapeutic effect. The combination of PLA with pelvic irradiation, when regional metastases have already occurred (23 patients), may be fit for localizing the tumour process, since the survival rates, compared to those of the pN0 group, showed no significant difference. For that reason, furthermore for the difficulty to determine the N category accurately by conventional methods, it is recommended to perform PLA prior to radiation monotherapy.
对181例接受单纯放疗的前列腺癌患者进行了盆腔淋巴结清扫术（PLA）的治疗效果测试。67例属于pN0类别的患者构成了一个高度选择性的组，其7年生存率为89%。在常规排除淋巴源性宏观转移、可能存在微转移的情况下，对81例患者进行盆腔照射的局部放疗也产生了同样好的效果。在常规证实存在区域淋巴源性宏观转移的情况下进行扩大盆腔照射仍无治疗效果。当已经发生区域转移时（23例患者），PLA与盆腔照射联合使用可能适合于定位肿瘤进程，因为与pN0组相比，生存率没有显著差异。因此，此外由于难以通过传统方法准确确定N类别，建议在单纯放疗之前进行PLA。
