Key Laboratory of Optical Field Manipulation of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou 310018, China.
School of Physics and Electronics Engineering, Fuyang Normal University, Fuyang 236037, China.
Biosensors (Basel). 2022 Dec 31;13(1):67. doi: 10.3390/bios13010067.
Sweat-rate measurement has received more and more attention, especially for specific groups, such as athletes, soldiers and manual workers, due to their excessive sweat loss under prolonged intense heat stress, which increases the risk of dehydration and electrolyte imbalance. The highly effective manufacture of a sweat-sensing device is essential to its wide range of applications in perspiration-related physiological information detection. In this work, we propose a simple and cost-effective strategy for the manufacture of a microfluidic sweat-rate-sensing patch via laser cutting and transfer printing technology. A copper foil tape is used as the electrode for in situ admittance based sweat-rate-sensing. The detection circuits and measurement conditions are optimized to prevent the negative effect of an electrochemical reaction between a copper electrode and sweat for precise admittance measurement. In vitro and on-body experiments demonstrate that the copper electrode is applicable for admittance-based sweat sensing and is capable of achieving equivalent sensing accuracy as a gold electrode and that the proposed sensor structure can perform consecutive and accurate sweat-rate-sensing and facilitates a significant increase in manufacturing efficiency.
排汗率的测量受到了越来越多的关注，特别是对于运动员、士兵和体力劳动者等特定群体，因为在长时间的强烈热应激下，他们会流失过多的汗液，这增加了脱水和电解质失衡的风险。高效制造汗液感应装置对于其在与出汗相关的生理信息检测中的广泛应用至关重要。在这项工作中，我们提出了一种通过激光切割和转印技术制造微流控排汗率感应贴片的简单且具有成本效益的策略。铜箔胶带被用作基于原位导纳的排汗率感应的电极。优化了检测电路和测量条件，以防止铜电极与汗液之间的电化学反应对精确导纳测量的负面影响。体外和体内实验表明，铜电极适用于基于导纳的汗液感应，并且能够实现与金电极相当的感应精度，并且所提出的传感器结构能够进行连续且准确的排汗率感应，并显著提高制造效率。
