叙利亚一组患者中幽门螺杆菌感染与毛舌病变之间可能的相关性评估：一项横断面试点研究。

Assessment of the Possible Correlation between the Presence of Helicobacter Pylori Infection and Hairy Tongue Lesion in a Group of Patients in Syria: A Cross-Sectional and Pilot Study.

作者信息

Sawan Dania, Mashlah Ammar M, Hajeer Mohammad Younis, Aljoujou Abeer A

机构信息

Department of Oral Medicine, College of Dentistry, Damascus University, Damascus MY1 HAJ72, Syria.

Department of Orthodontics, College of Dentistry, Damascus University, Damascus MY1 HAJ72, Syria.

出版信息

Int J Environ Res Public Health. 2023 Jan 11;20(2):1324. doi: 10.3390/ijerph20021324.

DOI:10.3390/ijerph20021324

PMID:36674080

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9859221/

Abstract

BACKGROUND

This study aimed to evaluate the correlation between the presence of hairy tongue and infection in patients referring to their blood test based on the serum levels of anti- IgG antibodies.

METHODS

This cross-sectional study was conducted in the Department of Oral Medicine, University of Damascus Dental School, between February 2021 and January 2022. The sample size of 40 patients (23 males, 17 females), whose ages ranged from 20-79 years with a mean age of 41.5 ± 12 years, was calculated using the G*power 3.1.3, with a statistical power of 80% and a significance level of 0.05. The hairy tongue index was assessed by a visual method based on observing the dorsum tongue appearance. Then, a blood test was performed to detect the presence of by Immulite 2000 XPi. Statistical analysis was performed using SPSS software 22.0, Chi-square.

RESULTS

The prevalence of hairy tongue was higher among males (75%) as compared to females (25%) and was found to be statistically significant ( = 0.026). The hairy tongue lesions were found to be least in the 20-39 age group and most prevalent in the 40-59 age group, without statistically significant correlation. infection was detected positive in 70% and negative in 30% of hairy tongue patients, compared to the control group, where the rates were 15% and 85%, respectively, with a statistically significant correlation between infection with and hairy tongue ( = 0.001).

CONCLUSION

Our results strongly suggest that the hairy tongue might be considered an indicator of infection.

摘要

背景

本研究旨在基于抗IgG抗体的血清水平，评估前来进行血液检测的患者中毛舌的存在与感染之间的相关性。

方法

本横断面研究于2021年2月至2022年1月在大马士革大学牙科学院口腔医学系进行。使用G*power 3.1.3计算样本量为40例患者（23例男性，17例女性），年龄范围为20 - 79岁，平均年龄为41.5±12岁，统计功效为80%，显著性水平为0.05。通过观察舌背外观的视觉方法评估毛舌指数。然后，进行血液检测以通过Immulite 2000 XPi检测[具体病原体]的存在。使用SPSS软件22.0进行卡方统计分析。

结果

男性毛舌患病率（75%）高于女性（25%），差异具有统计学意义（P = 0.026）。发现毛舌病变在20 - 39岁年龄组最少，在40 - 59岁年龄组最普遍，但无统计学显著相关性。与对照组相比，毛舌患者中[具体病原体]感染检测阳性率为70%，阴性率为30%，对照组的阳性率和阴性率分别为15%和85%，[具体病原体]感染与毛舌之间存在统计学显著相关性（P = 0.001）。