衰弱与炎症性肠病：当前证据的范围综述
Frailty and Inflammatory Bowel Disease: A Scoping Review of Current Evidence.
作者信息
Fons Anne, Kalisvaart Kees, Maljaars Jeroen
机构信息
Department of Gastroenterology and Hepatology, Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands.
Department of Geriatric Medicine, Spaarne Gasthuis, 2035 RC Haarlem, The Netherlands.
出版信息
J Clin Med. 2023 Jan 9;12(2):533. doi: 10.3390/jcm12020533.
Frailty is increasingly recognized as an important concept in patients with Inflammatory Bowel Disease (IBD). The aim of this scoping review is to summarize the current literature on frailty in IBD. We will discuss the definition of frailty, frailty assessment methods, the prevalence of frailty, risk factors for frailty and the prognostic value of frailty in IBD. A scoping literature search was performed using the PubMed database. Frailty prevalence varied from 6% to 53.9%, depending on the population and frailty assessment method. Frailty was associated with a range of adverse outcomes, including an increased risk for all-cause hospitalization and readmission, mortality in non-surgical setting, IBD-related hospitalization and readmission. Therefore, frailty assessment should become integrated as part of routine clinical care for older patients with IBD.
衰弱日益被认为是炎症性肠病（IBD）患者的一个重要概念。本综述的目的是总结当前关于IBD患者衰弱的文献。我们将讨论衰弱的定义、衰弱评估方法、衰弱的患病率、衰弱的危险因素以及衰弱在IBD中的预后价值。使用PubMed数据库进行了文献综述。根据人群和衰弱评估方法的不同，衰弱患病率在6%至53.9%之间。衰弱与一系列不良结局相关，包括全因住院和再入院风险增加、非手术环境下的死亡率、IBD相关住院和再入院。因此，衰弱评估应成为老年IBD患者常规临床护理的一部分。
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