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光疗在成人和儿童医学中作为治疗皮肤病、癌症、美容皮肤病及变应性鼻炎的方法

Phototherapy as a Treatment for Dermatological Diseases, Cancer, Aesthetic Dermatologic Conditions and Allergenic Rhinitis in Adult and Paediatric Medicine.

作者信息

Kennedy Roy

机构信息

Warwickshire College University Centre, Warwick New Road, Royal Leamington Spa, Warwickshire CV32 5JE, UK.

出版信息

Life (Basel). 2023 Jan 9;13(1):196. doi: 10.3390/life13010196.

DOI:10.3390/life13010196
PMID:36676145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9864074/
Abstract

The development of light-emitting diodes (LEDs) has led to an increase in the use of lighting regimes within medicine particularly as a treatment for dermatological conditions. New devices have demonstrated significant results for the treatment of medical conditions, including mild-to-moderate acne vulgaris, wound healing, psoriasis, squamous cell carcinoma in situ (Bowen's disease), basal cell carcinoma, actinic keratosis, and cosmetic applications. The three wavelengths of light that have demonstrated several therapeutic applications are blue (415 nm), red (633 nm), and near-infrared (830 nm). This review shows their potential for treating dermatological conditions. Phototherapy has also been shown to be an effective treatment for allergenic rhinitis in children and adults. In a double-anonymized randomized study it was found that there was 70% improvement of clinical symptoms of allergic rhinitis after intranasal illumination by low-energy narrow-band phototherapy at a wavelength of 660 nm three times a day for 14 consecutive days. Improvement of oedema in many patients with an age range of 7-17 were also observed. These light treatments can now be self-administered by sufferers using devices such as the Allergy Reliever phototherapy device. The device emits visible light (mUV/VIS) and infra-red light (660 nm and 940 nm) wavelengths directly on to the skin in the nasal cavity for a 3 min period. Several phototherapy devices emitting a range of wavelengths have recently become available for use and which give good outcomes for some dermatological conditions.

摘要

发光二极管(LED)的发展使得医学领域对照明疗法的使用有所增加,尤其是用于治疗皮肤病。新设备已在治疗多种病症方面取得显著成效,包括轻度至中度寻常痤疮、伤口愈合、牛皮癣、原位鳞状细胞癌(鲍恩病)、基底细胞癌、光化性角化病以及美容应用。已证明具有多种治疗应用的三种光波长分别为蓝光(415纳米)、红光(633纳米)和近红外光(830纳米)。本综述展示了它们在治疗皮肤病方面的潜力。光疗法也已被证明是治疗儿童和成人过敏性鼻炎的有效方法。在一项双盲随机研究中发现,连续14天每天三次采用波长为660纳米的低能量窄带光疗法进行鼻腔照射后,过敏性鼻炎的临床症状改善了70%。还观察到许多年龄在7至17岁的患者水肿情况有所改善。现在患者可以使用诸如“过敏缓解器”光疗设备等自行进行这些光治疗。该设备可将可见光(中紫外/可见光)和红外光(660纳米和940纳米)波长直接照射到鼻腔皮肤3分钟。最近有几种发射一系列波长的光疗设备可供使用,并且在一些皮肤病治疗方面取得了良好效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f65c/9864074/257b69c7facf/life-13-00196-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f65c/9864074/257b69c7facf/life-13-00196-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f65c/9864074/257b69c7facf/life-13-00196-g001.jpg

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本文引用的文献

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Phototherapy in dermatological maladies (Review).皮肤病中的光疗(综述)
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Blue Light in Dermatology.皮肤科中的蓝光
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Study on the effect of phototherapy for inhibition of symptoms associated with allergic rhinitis.研究光疗抑制过敏性鼻炎相关症状的效果。
Eur Ann Allergy Clin Immunol. 2020 Mar;52(2):66-73. doi: 10.23822/EurAnnACI.1764-1489.111. Epub 2019 Oct 8.
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Phototherapy with Light Emitting Diodes: Treating a Broad Range of Medical and Aesthetic Conditions in Dermatology.发光二极管光疗法:治疗皮肤科广泛的医学和美容病症
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Visible Blue Light Therapy: Molecular Mechanisms and Therapeutic Opportunities.可见蓝光疗法:分子机制与治疗机遇。
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