Vázquez-Lorente Héctor, Herrera-Quintana Lourdes, Molina-López Jorge, López-González Beatriz, Planells Elena
Department of Physiology, Faculty of Pharmacy, Institute of Nutrition and Food Technology "José Mataix", University of Granada, 18071 Granada, Spain.
Faculty of Education, Psychology and Sports Sciences, University of Huelva, 21007 Huelva, Spain.
Metabolites. 2023 Jan 3;13(1):78. doi: 10.3390/metabo13010078.
Postmenopausal aging has become relevant for understanding health during the transition life stages-the aging process being involved in several disturbances of the human condition. The present study aimed to investigate the relationship between postmenopausal aging and sociodemographic, anthropometric, body composition, nutritional, and biochemical (i.e., protein and lipid profiles, phosphorous-calcium metabolism, and antioxidant status) factors in postmenopausal women. This cross-sectional study enrolled 78 healthy postmenopausal women (44-76 years). The anthropometrical data showed no differences by age. Biochemical parameters, especially those involved in the protein and phosphorous-calcium metabolism, were influenced by age in our cohort of postmenopausal women. In contrast, no associations were found when considering lipid and antioxidant parameters. Height, fiber intake, blood glucose, protein profile and phosphorous-calcium metabolism markers seem to be the most affected nutritional-related factors by age in our cohort of healthy postmenopausal women. Primary prevention strategies focused on parameters at risk of disruption with postmenopausal aging are necessary to ensure the quality of life in older ages.
绝经后衰老已成为理解生命过渡阶段健康状况的重要因素——衰老过程涉及人类状况的多种紊乱。本研究旨在调查绝经后衰老与绝经后女性的社会人口统计学、人体测量学、身体成分、营养和生化(即蛋白质和脂质谱、磷钙代谢和抗氧化状态)因素之间的关系。这项横断面研究招募了78名健康的绝经后女性(44 - 76岁)。人体测量数据在各年龄组间无差异。在我们的绝经后女性队列中,生化参数,尤其是那些参与蛋白质和磷钙代谢的参数,受年龄影响。相比之下,在考虑脂质和抗氧化参数时未发现关联。在我们的健康绝经后女性队列中,身高、纤维摄入量、血糖、蛋白质谱和磷钙代谢标志物似乎是受年龄影响最大的营养相关因素。关注有绝经后衰老导致紊乱风险的参数的一级预防策略对于确保老年人的生活质量至关重要。