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天然肽的提取、修饰和合成及其对皮肤的有益作用综述。

Review on Extraction, Modification, and Synthesis of Natural Peptides and Their Beneficial Effects on Skin.

机构信息

College of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.

College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun 130118, China.

出版信息

Molecules. 2023 Jan 16;28(2):908. doi: 10.3390/molecules28020908.

Abstract

Peptides, functional nutrients with a size between those of large proteins and small amino acids, are easily absorbed by the human body. Therefore, they are seeing increasing use in clinical medicine and have revealed immunomodulatory and anti-inflammatory properties which could make them effective in healing skin wounds. This review sorted and summarized the relevant literature about peptides during the past decade. Recent works on the extraction, modification and synthesis of peptides were reviewed. Importantly, the unique beneficial effects of peptides on the skin were extensively explored, providing ideas for the development and innovation of peptides and laying a knowledge foundation for the clinical application of peptides.

摘要

肽是一种大小介于大蛋白质和小氨基酸之间的功能性营养素,容易被人体吸收。因此,它们在临床医学中的应用越来越广泛,并表现出免疫调节和抗炎特性,这使得它们在治疗皮肤伤口方面具有有效性。本综述对过去十年中有关肽的相关文献进行了分类和总结。综述了肽的提取、修饰和合成的最新研究进展。重要的是,广泛探讨了肽对皮肤的独特有益作用,为肽的开发和创新提供了思路,为肽的临床应用奠定了知识基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fce7/9863410/18e45862905b/molecules-28-00908-g001.jpg

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