Department of Obstetrics and Gynecology, General Hospital Zadar, Bože Peričića 5, 23000, Zadar, Croatia.
Department of Obstetrics and Gynecology, University Hospital Center Zagreb, Zagreb, Croatia.
Arch Gynecol Obstet. 2023 Jul;308(1):231-237. doi: 10.1007/s00404-023-06918-9. Epub 2023 Jan 21.
We conducted an observational single-center cohort study on patients with recurrent high-grade serous ovarian carcinoma that underwent secondary surgical cytoreduction with extent of partial ileectomy and/or colectomy, followed by adjuvant chemotherapy (Paclitaxel-Carboplatin). All patients performed previously primary debulking surgery without residual disease, followed by three cycles of adjuvant chemotherapy. The aim of this study was to compare survival in patients with ostomy or end-to-end anastomosis that underwent secondary cytoreduction. Furthermore, we investigated the morbidity, the rate, timing and complications of the ostomy or end-to-end anastomosis after secondary cyto-reduction.
我们进行了一项观察性单中心队列研究，纳入了接受二次手术减瘤术的复发性高级别浆液性卵巢癌患者，手术范围包括部分回肠切除术和/或结肠切除术，随后进行辅助化疗（紫杉醇-卡铂）。所有患者均曾行初次肿瘤细胞减灭术且无残留病灶，随后接受了 3 个周期的辅助化疗。本研究旨在比较行二次细胞减瘤术后行造口术或端端吻合术患者的生存情况。此外，我们还研究了二次细胞减瘤术后造口术或端端吻合术的发病率、吻合口的形成率、吻合口形成的时间和并发症。
