Hansbrough J R, Wedner H J, Chaplin D D
Howard Hughes Medical Institute Laboratories, Washington University School of Medicine, St. Louis, Mo 63110.
J Allergy Clin Immunol. 1987 Oct;80(4):538-41. doi: 10.1016/0091-6749(87)90004-2.
A patient with long-standing hypertension developed urticaria, angioedema, and hypotension within 5 minutes after the intravenous administration of furosemide. Immediate hypersensitivity was documented by positive skin tests to furosemide as well as to related sulfonamide-based drugs. This is the first finding of an anaphylactic reaction to furosemide and underscores the need to consider such adverse reactions when patients who are sensitive to other sulfonamide-containing drugs are being treated.
一名患有长期高血压的患者在静脉注射呋塞米后5分钟内出现荨麻疹、血管性水肿和低血压。对呋塞米以及相关磺胺类药物的皮肤试验呈阳性，证实了速发型超敏反应。这是首次发现对呋塞米的过敏反应，强调了在治疗对其他含磺胺类药物敏感的患者时需要考虑此类不良反应。
