School of Biomedical and Precision Engineering, University of Bern, 3008 Bern, Switzerland; Graduate School for Cellular and Biomedical Sciences, University of Bern, 3012 Bern, Switzerland.
Department of Cardiology, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland; ARTORG Center for Biomedical Engineering Research, University of Bern, 3008 Bern, Switzerland; Swiss Institute for Translational and Entrepreneurial Medicine, 3010 Bern, Switzerland.
Ultrasonics. 2023 Apr;130:106927. doi: 10.1016/j.ultras.2023.106927. Epub 2023 Jan 6.
This paper introduces a titanium-based planar ultrasonic microscalpel. The concept of silicon-based planar ultrasonic transducers has already been proven, but they are not yet suitable for clinical use due to material failure. The main objective of this work was to develop a smaller, lighter, and more cost-effective ultrasonic scalpel that could be used as an alternative or supplementary device to current surgical instruments. Various prototypes were fabricated and characterized, differing in bonding by three epoxy adhesives and two solder pastes as well as three variations in tip design. The instruments were designed to operate in the frequency range of commercial instruments and to generate a longitudinal displacement amplitude. The electro-mechanical characterization through impedance analysis and vibration measurements was complemented by an in vitro cutting trial and an acute in vivo animal experiment in comparison to commercial ultrasonic and electrosurgical devices. The operating frequency was around 40 kHz and 48 kHz depending on whether matched or unmatched operation was used. Unmatched operation turned out to be more suitable, achieving displacement amplitudes of 25.3 μm and associated velocity amplitudes of up to 7.9 m/s at an electrical power of 10.2 W. The cutting ability was demonstrated in vivo by successful dissection even under anticoagulation. The geometry of the instrument tip was found to have a major influence on cutting performance by affecting the resonance behaviour and tissue penetration.
本文介绍了一种基于钛的平面超声手术刀。基于硅的平面超声换能器的概念已经得到证实，但由于材料失效，它们还不适用于临床应用。这项工作的主要目标是开发一种更小、更轻、更具成本效益的超声手术刀，可以作为现有手术器械的替代或补充设备。制作并表征了各种原型，它们在键合方面有所不同，分别采用了三种环氧树脂胶和两种焊锡膏，以及三种不同的刀尖设计。这些仪器的设计目的是在商业仪器的频率范围内运行，并产生纵向位移振幅。通过阻抗分析和振动测量进行的机电特性表征，辅以体外切割试验和与商业超声和电外科设备的急性体内动物实验进行了补充。工作频率约为 40 kHz 和 48 kHz，具体取决于使用匹配还是不匹配操作。不匹配操作结果更适合，在 10.2 W 的电功率下实现了 25.3 μm 的位移幅度和高达 7.9 m/s 的相关速度幅度。在抗凝条件下，体内成功的解剖证明了该仪器的切割能力。研究发现，仪器刀尖的几何形状通过影响共振行为和组织穿透对切割性能有重大影响。
