Suppr超能文献

妊娠性白细胞增多症:一例报告。

Pregnancy-induced leukocytosis: A case report.

作者信息

Wang Xi, Zhang Yang-Yang, Xu Yang

机构信息

Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China.

出版信息

World J Clin Cases. 2022 Dec 26;10(36):13349-13355. doi: 10.12998/wjcc.v10.i36.13349.

Abstract

BACKGROUND

Pregnancy is a complex physiological process. Physiological leukocytosis occurs often and is mainly associated with increased neutrophil counts, especially in the third trimester of pregnancy. Non-congenital leukocytosis with white blood cell counts above 20 × 10/L lasting 13 wk during pregnancy is rare and has been reported occasionally. Herein, we present a case of pregnancy-induced leukocytosis.

CASE SUMMARY

We present the case of a 33-year-old Chinese woman at 27 wk of gestation who had a leukocytosis complication. No abnormalities were detected in the examinations before pregnancy or in the first trimester. From the third trimester of pregnancy, the patient began to suffer from asymptomatic leukocytosis. We administered antibiotics to treat the patient; however, the complication persisted until the patient underwent a cesarean section after 40 wk of gestation. One day after the cesarean section, the patient's neutrophil count returned to normal. After 2 years of follow-up, we found that the patient and baby were healthy.

CONCLUSION

Pregnancy-induced leukocytosis seems to be associated with immunoregulation and pregnancy termination may be the most effective treatment approach for pregnancies complicated with malignant leukocytosis.

摘要

背景

妊娠是一个复杂的生理过程。生理性白细胞增多症较为常见,主要与中性粒细胞计数增加有关,尤其是在妊娠晚期。孕期白细胞计数高于20×10⁹/L且持续13周的非先天性白细胞增多症较为罕见,仅有偶尔的病例报道。在此,我们报告一例妊娠诱发的白细胞增多症病例。

病例摘要

我们报告一例33岁中国女性,孕27周时出现白细胞增多症并发症。孕前及孕早期检查均未发现异常。从妊娠晚期开始,患者出现无症状性白细胞增多症。我们给予患者抗生素治疗,但并发症持续存在,直至患者孕40周行剖宫产术后。剖宫产术后一天,患者中性粒细胞计数恢复正常。经过2年随访,我们发现患者和婴儿均健康。

结论

妊娠诱发的白细胞增多症似乎与免疫调节有关,对于合并恶性白细胞增多症的妊娠,终止妊娠可能是最有效的治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57ed/9851002/a8e58ff0e7f6/WJCC-10-13349-g001.jpg

相似文献

1
Pregnancy-induced leukocytosis: A case report.
World J Clin Cases. 2022 Dec 26;10(36):13349-13355. doi: 10.12998/wjcc.v10.i36.13349.
2
Pregnancy complicated with agranulocytosis.
Medicine (Baltimore). 2016 Dec;95(52):e5717. doi: 10.1097/MD.0000000000005717.
3
Can leukocyte count during the first trimester of pregnancy predict later gestational complications?
Arch Gynecol Obstet. 2013 Mar;287(3):421-7. doi: 10.1007/s00404-012-2603-0. Epub 2012 Oct 19.
5
[Heart transplantations: impact on female fertility].
Bull Acad Natl Med. 1991 Apr;175(4):531-40; discussion 540-5.
6
Haematological effects of betamethasone treatment in late pregnancy.
Aust N Z J Obstet Gynaecol. 1998 Nov;38(4):396-8. doi: 10.1111/j.1479-828x.1998.tb03095.x.
7
A Case Report of Leukocytosis During Modified Electroconvulsive Therapy of Paranoid Personality Disorder.
Front Psychiatry. 2022 May 26;13:899847. doi: 10.3389/fpsyt.2022.899847. eCollection 2022.
8
Carbamazepine-induced leukocytosis.
Am J Hosp Pharm. 1980 Apr;37(4):550-2.
9
Successful pregnancy outcome in a case of eisenmenger syndrome: a rare case report.
J Clin Diagn Res. 2014 Oct;8(10):OD08-9. doi: 10.7860/JCDR/2014/9120.5050. Epub 2014 Oct 20.
10
Rupture of a myomectomy site in the third trimester of pregnancy after myomectomy, septoplasty and cesarean section: A case report.
Case Rep Womens Health. 2018 May 30;19:e00066. doi: 10.1016/j.crwh.2018.e00066. eCollection 2018 Jul.

本文引用的文献

2
Pregnancy complicated with agranulocytosis.
Medicine (Baltimore). 2016 Dec;95(52):e5717. doi: 10.1097/MD.0000000000005717.
5
Plasma electrolyte and hematological changes after marathon running in adolescents.
Med Sci Sports Exerc. 2013 Jun;45(6):1182-7. doi: 10.1249/MSS.0b013e3182831a93.
6
[The role of infection in preterm birth].
J Gynecol Obstet Biol Reprod (Paris). 2012 Feb;41(1):14-25. doi: 10.1016/j.jgyn.2011.10.004. Epub 2011 Dec 20.
7
Immune regulation of conception and embryo implantation-all about quality control?
J Reprod Immunol. 2010 May;85(1):51-7. doi: 10.1016/j.jri.2010.01.008. Epub 2010 Mar 27.
8
Limited reliability of the indirect immunofluorescence technique for the detection of anti-Rib-P antibodies.
Arthritis Res Ther. 2008;10(6):R131. doi: 10.1186/ar2548. Epub 2008 Nov 11.
9
Total and differential leukocyte counts percentiles in normal pregnancy.
Eur J Obstet Gynecol Reprod Biol. 2008 Jan;136(1):16-9. doi: 10.1016/j.ejogrb.2006.12.013. Epub 2007 Feb 2.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验