Al Khayyat Suhel Gabriele, Conticini Edoardo, Falsetti Paolo, Gentileschi Stefano, Vitale Antonio, Stella Salvatore Massimo, D'Alessandro Miriana, Bargagli Elena, Cantarini Luca, Frediani Bruno
Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy.
Advanced Musculoskeletal Ultrasound, SIUMB School of Pisa, Italy.
Reumatologia. 2022;60(6):422-436. doi: 10.5114/reum.2022.123672. Epub 2022 Dec 30.
Among the rheumatic diseases whose symptoms are more often associated with the possibility of cancer and other malignancies are systemic sclerosis, dermatomyositis and rheumatic polymyalgia. However, a differential diagnosis should be performed in each case of non-typical rheumatic disease and/or other neoplastic disease risk factors. The article's aim was based on a literature review of this subject and presentation own a case description and discussion about arthritis as a paraneoplastic syndrome. The conclusions of our analysis were as follows: more often paraneoplastic arthritis occurs in men, in ages higher than 50 years old, in patients who poorly respond to treatment of arthritis with polyarticular symmetrical involvement of the limbs, seronegative type of inflammatory joint disease. In this group of patients, complete remission after treatment of the primary tumor and recurrence of the symptoms in the presence of metastasis was observed.
在症状更常与癌症及其他恶性肿瘤可能性相关的风湿性疾病中,有系统性硬化症、皮肌炎和风湿性多肌痛。然而,对于每一例非典型风湿性疾病和/或其他肿瘤性疾病风险因素的病例,都应进行鉴别诊断。本文的目的基于对该主题的文献综述,并呈现了一个关于关节炎作为副肿瘤综合征的病例描述及讨论。我们的分析结论如下:副肿瘤性关节炎更常发生于男性、50岁以上人群、对四肢多关节对称性受累的关节炎治疗反应不佳的患者、血清阴性类型的炎性关节病患者。在这组患者中,观察到原发性肿瘤治疗后完全缓解以及出现转移时症状复发的情况。