Zhang Yuyang, Zhou Qingqing, Chen Zeyang, Dong Jie, Wang Pengyuan
Department of General Surgery, Peking University First Hospital, Beijing, Republic of China.
Renal Division, Department of Medicine, Peking University First Hospital, Beijing, Republic of China.
Front Surg. 2023 Jan 6;9:1056908. doi: 10.3389/fsurg.2022.1056908. eCollection 2022.
The associations between preoperative transfer to hemodialysis (HD) and postoperative outcomes in patients on chronic peritoneal dialysis (PD) remain unknown. We conducted this retrospective cohort study to investigate whether preoperative HD could influence surgical outcomes in PD patients undergoing major surgeries.
All chronic PD patients who underwent major surgeries from January 1, 2007, to December 31, 2020, at Peking University First Hospital were screened. Major surgery was defined as surgical procedures under general, lumbar or epidural anesthesia, with more than an overnight hospital stay. Patients under the age of 18, with a dialysis duration of less than 3 months, and those who underwent renal implantation surgeries and procedures exclusively aimed at placing or removing PD catheters were excluded. Patients involved were divided into either HD or PD group based on their preoperative dialysis status for further analysis.
Of 105 PD patients enrolled, 65 continued PD, and 40 switched to HD preoperatively. Patients with preoperative HD were significantly more likely to develop postoperative hyperkalemia. The total complication rates were numerically higher in patients undergoing preoperative HD. After adjustment, the incidence of postoperative hyperkalemia or any other postoperative complication rates were similar between groups. There were no differences in long-term survival between the two groups.
It does not seem indispensable for PD patients to switch to temporary HD before major surgeries.
慢性腹膜透析(PD)患者术前转为血液透析(HD)与术后结局之间的关联尚不清楚。我们进行了这项回顾性队列研究,以调查术前HD是否会影响接受大手术的PD患者的手术结局。
筛选2007年1月1日至2020年12月31日在北京大学第一医院接受大手术的所有慢性PD患者。大手术定义为在全身、腰部或硬膜外麻醉下进行的手术,住院时间超过一夜。排除年龄小于18岁、透析时间少于3个月以及接受肾脏植入手术和专门旨在放置或移除PD导管的手术的患者。根据术前透析状态将纳入的患者分为HD组或PD组进行进一步分析。
在纳入的105例PD患者中,65例继续进行PD,40例术前转为HD。术前进行HD的患者术后发生高钾血症的可能性显著更高。术前进行HD的患者的总并发症发生率在数值上更高。调整后,两组之间术后高钾血症或任何其他术后并发症发生率相似。两组的长期生存率没有差异。
对于PD患者而言,在大手术前转为临时HD似乎并非必不可少。