Garlaschi Alessandro, Valente Irene, Brunetti Nicole, De Giorgis Sara, Massa Barbara, Calabrese Massimo, Tagliafico Alberto Stefano
aIRCCS Ospedale Policlinico San Martino, Genoa, Italy.
bOspedale Maggiore di Parma, Parma, Italy.
Breast Care (Basel). 2022 Oct;17(5):443-449. doi: 10.1159/000523909. Epub 2022 Mar 7.
Vacuum-assisted breast biopsy (VABB) is a safe procedure comparable to surgical biopsy for the characterization of distortions, microcalcifications, and mass lesions. Vacuum-assisted excision of T1 breast tumors could be on potential management in alternative to surgery. The primary objective of this work was to assess the therapeutic success of the stereotaxic vacuum breast biopsy in small breast cancer (T1N0M0) lesions excision.
From our electronic database, all the vacuum breast biopsies performed from January 1, 2015, to December 1, 2019, have been retrospectively reevaluated. = 2,200 cases were identified and = 145 ensured "mammographic complete removal" at the end of vacuum-assisted excision treatment and were considered for analysis. Surgical gold standard was used.
= 143 procedures were successfully completed with complete removal of mammographic calcifications. The mean size of the lesions completely excised with VABB was 8.9 ± 3.6 mm (range, 3-23 mm). Lesions below 10 mm were = 118 and lesion with diameter >10 mm were = 28. = 3/146 cases (4.4%), relapses were observed in follow-up (at 12-24 up to a maximum of 60 months): the mean size of relapsed lesions completely excised was 3.6 ± 2.1 mm (range, 2-6 mm). No relapse before 12 months were observed. The mean size of the lesions in these patients with relapse at the time of the first VABB procedures was 13 ± 6.5 mm (range, 7-12 mm). = 117/118 (99%) lesions excised using VABB without relapse after 1 year of follow-up had a diameter below 10 mm.
Vacuum breast biopsy could safely remove small breast cancers (T1N0M0) with few relapses.
真空辅助乳腺活检（VABB）是一种安全的检查方法，在对乳腺结构扭曲、微钙化及肿块病变的特征描述方面，与手术活检效果相当。对于T1期乳腺肿瘤，真空辅助切除可作为手术之外的一种潜在治疗方式。本研究的主要目的是评估立体定位真空辅助乳腺活检在切除小乳腺癌（T1N0M0）病变中的治疗效果。
从我们的电子数据库中，对2015年1月1日至2019年12月1日期间进行的所有真空辅助乳腺活检进行回顾性重新评估。共识别出2200例病例，其中145例在真空辅助切除治疗结束时确保达到“乳腺钼靶完全切除”，并纳入分析。采用手术金标准。
143例手术成功完成，乳腺钼靶钙化完全清除。经VABB完全切除的病变平均大小为8.9±3.6mm（范围3 - 23mm）。直径小于10mm的病变有118例，直径大于10mm的病变有28例。在随访中（12 - 24个月，最长60个月）观察到3/146例（4.4%）复发：复发病变完全切除后的平均大小为3.6±2.1mm（范围2 - 6mm）。12个月前未观察到复发。首次VABB手术时这些复发患者的病变平均大小为13±6.5mm（范围7 - 12mm）。随访1年后，117/118例（99%）经VABB切除且未复发的病变直径小于10mm。
真空辅助乳腺活检能够安全地切除小乳腺癌（T1N0M0），复发率低。
