Regoli François D, Cattaneo Mattia, Kola Florenc, Thartori Albana, Bytyci Hekuran, Saccarello Luca, Amoruso Marco, Di Valentino Marcello, Menafoglio Andrea
Cardiology Service, Ospedale San Giovanni, Cardiocentro Institute, Ente Ospedaliero Cantonale, Bellinzona, Switzerland.
Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Lugano, Switzerland.
Front Cardiovasc Med. 2023 Jan 4;9:1011619. doi: 10.3389/fcvm.2022.1011619. eCollection 2022.
Management of hemodynamically stable, incessant wide QRS complex tachycardia (WCT) in patients who already have an implantable cardioverter defibrillator (ICD) is challenging. First-line treatment is performed by medical staff who have no knowledge on programmed ICD therapy settings and there is always some concern for unexpected ICD shock. In these patients, a structured approach is necessary from presentation to therapy. The present review provides a systematic approach in four distinct phases to guide any physician involved in the management of these patients: PHASE I: assessment of hemodynamic status and use of the magnet to temporarily suspend ICD therapies, especially shocks; identification of possible arrhythmia triggers; risk stratification in case of electrical storm (ES).
The preparation phase includes reversal of potential arrhythmia "triggers", mild patient sedation, and patient monitoring for therapy delivery. Based on resource availability and competences, the most adequate therapeutic approach is chosen. This choice depends on whether a device specialist is readily available or not. In the case of ES in a "high-risk" patient an accelerated patient management protocol is advocated, which considers urgent ventricular tachycardia transcatheter ablation with or without mechanical cardiocirculatory support.
Therapeutic phase is based on the use of intravenous anti-arrhythmic drugs mostly indicated in this clinical context are presented. Device interrogation is very important in this phase when sustained monomorphic VT diagnosis is confirmed, then ICD ATP algorithms, based on underlying VT cycle length, are proposed. In high-risk patients with intractable ES, intensive patient management considers MCS and transcatheter ablation.
The patient is hospitalized for further diagnostics and management aimed at preventing arrhythmia recurrences.
对于已经植入植入式心脏复律除颤器(ICD)的血流动力学稳定的持续性宽QRS波群心动过速(WCT)患者,其管理具有挑战性。一线治疗由不了解ICD程控治疗设置的医务人员进行,并且始终存在对意外ICD电击的担忧。在这些患者中,从就诊到治疗都需要一种结构化的方法。本综述提供了一个分四个不同阶段的系统方法,以指导参与这些患者管理的任何医生:
评估血流动力学状态并使用磁铁暂时中止ICD治疗,尤其是电击;识别可能的心律失常触发因素;在发生电风暴(ES)时进行风险分层。
准备阶段包括逆转潜在的心律失常“触发因素”、对患者进行轻度镇静以及监测患者以进行治疗。根据资源可用性和能力,选择最适当的治疗方法。这一选择取决于是否有设备专家随时可用。对于“高危”患者发生ES的情况,提倡采用加速患者管理方案,该方案考虑在有或没有机械心脏循环支持的情况下紧急进行室性心动过速经导管消融。
治疗阶段基于静脉使用抗心律失常药物,介绍了在此临床背景下最常用的药物。当确诊为持续性单形性室速时,设备询问在这一阶段非常重要,然后根据基础室速周期长度提出ICD抗心动过速起搏(ATP)算法。对于难治性ES的高危患者,强化患者管理考虑机械循环支持(MCS)和经导管消融。
患者住院进行进一步的诊断和管理,旨在预防心律失常复发。