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一名患有Brugada综合征和2019冠状病毒病患者的电风暴

Electrical Storm in a Patient with Brugada Syndrome and Coronavirus Disease 2019.

作者信息

Ali Syed H, Nilsson Kent R

机构信息

Department of Medicine, Medical College of Georgia at the Augusta University-University of Georgia Medical Partnership, Athens, GA, USA.

Department of Internal Medicine, Piedmont Heart Institute, Piedmont Athens Regional, Athens, GA, USA.

出版信息

J Innov Card Rhythm Manag. 2022 Jun 15;13(6):5019-5023. doi: 10.19102/icrm.2022.130601. eCollection 2022 Jun.

DOI:10.19102/icrm.2022.130601
PMID:35765584
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9221185/
Abstract

Brugada syndrome (BrS) is an inherited arrhythmia syndrome characterized by right bundle branch block and dynamic ST-segment changes in precordial leads V1-V3. In patients with BrS, fever is a known trigger that may induce arrhythmia. For patients with BrS who contract coronavirus disease 2019 (COVID-19), the inflammatory response poses the risk of causing ventricular arrhythmias. The following case discusses the management of a patient with BrS presenting with electrical storm after contracting COVID-19. Treatment should be focused on aggressive anti-pyretic management along with concomitant pharmacological therapy.

摘要

布加综合征（BrS）是一种遗传性心律失常综合征，其特征为右束支传导阻滞及胸前导联V1-V3动态ST段改变。在布加综合征患者中，发热是已知的可诱发心律失常的触发因素。对于感染2019冠状病毒病（COVID-19）的布加综合征患者，炎症反应有引发室性心律失常的风险。以下病例讨论了一名感染COVID-19后出现电风暴的布加综合征患者的治疗。治疗应侧重于积极的退热治疗及同时进行的药物治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efe7/9221185/7cd442a85b25/icrm-13-5019-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efe7/9221185/106807493261/icrm-13-5019-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efe7/9221185/7346dbda2af5/icrm-13-5019-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efe7/9221185/7cd442a85b25/icrm-13-5019-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efe7/9221185/106807493261/icrm-13-5019-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efe7/9221185/7346dbda2af5/icrm-13-5019-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/efe7/9221185/7cd442a85b25/icrm-13-5019-g003.jpg

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本文引用的文献

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Feasibility evaluation of long-term use of beta-blockers and calcium antagonists in patients with Brugada syndrome.评估 Brugada 综合征患者长期使用β受体阻滞剂和钙通道阻滞剂的可行性。
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Electrocardiographic Diagnosis of Brugada Syndrome in a Patient with Right Bundle Branch Block.右束支传导阻滞患者中Brugada综合征的心电图诊断
J Innov Card Rhythm Manag. 2022 Nov 15;13(11):5219-5220. doi: 10.19102/icrm.2022.13116. eCollection 2022 Nov.
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Exploring Coronavirus Disease 2019 and Brugada Syndrome.探索2019冠状病毒病与布加综合征。
J Innov Card Rhythm Manag. 2022 Jun 15;13(6):5025-5028. doi: 10.19102/icrm.2022.130607. eCollection 2022 Jun.
Front Cardiovasc Med. 2016 Apr 25;3:9. doi: 10.3389/fcvm.2016.00009. eCollection 2016.
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Genet Med. 2016 Jan;18(1):3-12. doi: 10.1038/gim.2015.35. Epub 2015 Apr 23.
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Use of ibuprofen to assess inflammatory biomarkers in induced sputum: Implications for clinical trials in cystic fibrosis.使用布洛芬评估诱导痰中的炎症生物标志物：对囊性纤维化临床试验的影响。
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