Chang Victor Ken On, Parry Nicholas McKay, Shoung Alex, Hsu Charlie Chia-Tsong
School of Medicine and Dentistry, Griffith University, Imaging, 1 Hospital Boulevard, Southport, Queensland, Australia.
Division of Neuroradiology, Department of Medical Imaging, Gold Coast University Hospital, Southport, Queensland, Australia.
Radiol Case Rep. 2023 Jan 6;18(3):1112-1116. doi: 10.1016/j.radcr.2022.11.076. eCollection 2023 Mar.
Burkitt's lymphoma follows a lymphogenous spread early in the disease. The central nervous system can be involved via a hematogenous route but involvement of the cavernous sinus (CS) is rare and can be misdiagnosed as other pathology of primary neoplastic, infective, or vascular origin. We present a case of a 73-year-old gentleman with painless jaundice and subjective heaviness to his eyes that progressed to partial ptosis of the left eye, complete ptosis of the right eye with diplopia, found to have disseminated Burkitt's lymphoma with bilateral deposits to the CS. Early recognition of Burkitt's lymphoma with CS involvement is important as it often signifies disseminated disease with implications on chemotherapy regimen, treatment outcomes, and survival.
伯基特淋巴瘤在疾病早期呈淋巴源性播散。中枢神经系统可通过血行途径受累,但海绵窦(CS)受累罕见,且可能被误诊为原发性肿瘤性、感染性或血管性起源的其他病变。我们报告一例73岁男性患者,其有无痛性黄疸及眼部主观沉重感,进而发展为左眼部分上睑下垂、右眼完全上睑下垂伴复视,经检查发现患有播散性伯基特淋巴瘤,双侧累及海绵窦。早期识别伴有海绵窦受累的伯基特淋巴瘤很重要,因为这往往意味着疾病已播散,对化疗方案、治疗结果及生存有影响。