Jayasekera Migara, Sartin Stephen, Bhargava Peeyush
Department of Radiology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, USA.
Radiol Case Rep. 2023 Jan 6;18(3):1046-1048. doi: 10.1016/j.radcr.2022.12.038. eCollection 2023 Mar.
This case report follows a 70-year-old male patient with Zollinger-Ellison syndrome undergoing computed tomography (CT) for weight loss and surveillance of bilateral adrenal nodules. Incidentally, diffuse gastric and duodenal wall thickening was noted on CT. The patient underwent esophagogastroduodenoscopy with biopsy results showing well-differentiated neuroendocrine tumors (NET) in the stomach and duodenum. Subsequent imaging with gallium-68 DOTATATE PET/CT showed intense tracer uptake in the stomach and proximal duodenum with liver and regional nodal metastases around the superior mesenteric artery. This case outlines the utility of Ga-68 DOTATATE PET/CT in diagnosing, localizing, and staging NET such as gastrinomas.
本病例报告的对象是一名70岁的男性患者，患有佐林格-埃利森综合征，因体重减轻及对双侧肾上腺结节进行监测而接受计算机断层扫描（CT）检查。偶然间，CT检查发现胃和十二指肠壁弥漫性增厚。该患者接受了食管胃十二指肠镜检查，活检结果显示胃和十二指肠存在高分化神经内分泌肿瘤（NET）。随后进行的镓-68 DOTATATE PET/CT成像显示，胃和十二指肠近端有强烈的示踪剂摄取，同时在肠系膜上动脉周围有肝脏和区域淋巴结转移。本病例概述了镓-68 DOTATATE PET/CT在诊断、定位和分期胃泌素瘤等神经内分泌肿瘤方面的应用。
