未在精神分裂症患者血清中检测到多巴胺受体IgG自身抗体。简短报告。
Failure to detect dopamine receptor IgG autoantibodies in sera of schizophrenic patients. Short note.
作者信息
von Kirchbach A, Fischer E G, Kornhuber H H
机构信息
Neurologische Universitätsklinik, Ulm, Federal Republic of Germany.
出版信息
J Neural Transm. 1987;70(1-2):175-9. doi: 10.1007/BF01252518.
PMID:3668519
Abstract
Autoantibodies against dopamine receptors in schizophrenic patients have been postulated. IgG was fractionated from sera of 15 schizophrenic patients (DSM III) in an acute episode. However, 3H-spiperone binding to dopamine receptors was not inhibited by this fraction.
摘要
已有研究推测精神分裂症患者体内存在针对多巴胺受体的自身抗体。从15例处于急性发作期的精神分裂症患者（DSM-III标准）血清中分离出免疫球蛋白G（IgG）。然而，该组分并未抑制3H-螺哌隆与多巴胺受体的结合。
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