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一例表现为弥漫性肺泡出血的既往未确诊的系统性红斑狼疮合并感染病例。

A Case of Previously Undiagnosed Systemic Lupus Erythematosus and Infection Presenting as Diffuse Alveolar Hemorrhage.

作者信息

Iqbal Henna, Screws Benny, Khan Muhammad S

机构信息

Biomedical Sciences Department, Mercer University School of Medicine, Macon, GA, USA.

Atrium Health (Navicent), Macon, GA, USA.

出版信息

Case Rep Rheumatol. 2023 Jan 11;2023:3686772. doi: 10.1155/2023/3686772. eCollection 2023.

Abstract

Diffuse alveolar hemorrhage (DAH) is described as the collection of blood in alveolar spaces caused by damaged pulmonary vasculature. It often presents as a life-threatening medical emergency that requires urgent medical intervention along with timely diagnosis and management of the underlying cause. We hereby report a 19-year-old female who presented with clinical and radiological characteristics consistent with DAH. Laboratory workup studies revealed a diagnosis of systemic lupus erythematosus (SLE) as well as (MTB) infection. This report describes an extremely unusual case of undiagnosed SLE and coexistent tuberculosis presenting as DAH. This leads to an interesting possibility of risks in patients with immune-mediated vasculitis towards developing severe pulmonary disease in the setting of pulmonary mycobacterial infection.

摘要

弥漫性肺泡出血(DAH)被描述为肺泡腔内血液的积聚,由受损的肺血管系统引起。它常表现为危及生命的医疗紧急情况,需要紧急医疗干预以及对潜在病因进行及时诊断和处理。我们在此报告一名19岁女性,其临床表现和影像学特征与DAH相符。实验室检查显示诊断为系统性红斑狼疮(SLE)以及结核分枝杆菌(MTB)感染。本报告描述了一例极为罕见的未确诊SLE与并存结核病表现为DAH的病例。这引发了一个有趣的可能性,即免疫介导性血管炎患者在肺部分枝杆菌感染情况下发生严重肺部疾病的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cbae/9848806/b0df9cb7e06d/CRIRH2023-3686772.001.jpg

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