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一例遗传性球形红细胞增多症患者出现可疑淋巴结病的罕见病例,报告为髓外造血。

A Curious Case of Suspicious Lymphadenopathy in a Hereditary Spherocytosis Patient Reported as Extramedullary Hematopoiesis.

作者信息

Khan Dikhra, Sharma Anshul, Sagar Sambit, Thayumanavan T, Kumar Rakesh

机构信息

Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Nucl Med. 2022 Jul-Sep;37(3):293-294. doi: 10.4103/ijnm.ijnm_10_22. Epub 2022 Nov 2.

Abstract

We present a case of a 23-year-old male patient with complaints of fever, cough, and persistent anemia for the past 6 months and with a known history of hereditary spherocytosis. Computed tomography (CT) thorax demonstrated multiple paravertebral lesions in the bilateral thoracic cavities, suggestive of lymphadenopathy; subsequently, Flurodeoxyglucose PET/CT was done with suspicion of lymphoma, which showed no significant metabolic activity in those lesions. Thus, in view of clinical and metabolic status, lesions were considered extramedullary hematopoiesis (EMH). This case highlights the importance of considering EMH, while interpreting suspicious lymphadenopathy in cases of chronic anemia and also possible scan findings in the same.

摘要

我们报告一例23岁男性患者,该患者在过去6个月中出现发热、咳嗽和持续性贫血症状,且有遗传性球形红细胞增多症病史。胸部计算机断层扫描(CT)显示双侧胸腔内多个椎旁病变,提示淋巴结病;随后,因怀疑淋巴瘤进行了氟脱氧葡萄糖PET/CT检查,结果显示这些病变无明显代谢活性。因此,鉴于临床和代谢状况,这些病变被认为是髓外造血(EMH)。该病例强调了在慢性贫血病例中解释可疑淋巴结病时考虑EMH的重要性,以及同一病例中可能的扫描结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a06/9855240/6fa5152ed216/IJNM-37-293-g001.jpg

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