Rossi M L, Bevan J S, Esiri M M, Hughes J T, Adams C B
Department of Neuropathology, Radcliffe Infirmary, Oxford, England.
J Neurosurg. 1987 Nov;67(5):768-72. doi: 10.3171/jns.1987.67.5.0768.
Tumors of the posterior pituitary are rare and the previous nomenclature has been confusing. A 40-year-old man presented with visual failure and disconnection hyperprolactinemia (830 mU/liter) due to a large invasive pituitary tumor shown to be a pituicytoma (pilocytic astrocytoma). Its astrocytic nature was confirmed by positive immunostaining for glial fibrillary acidic protein and the finding of cytoplasmic filaments on electron microscopy. This case report contains the pathological description of a pituicytoma and illustrates that a non-adenomatous pituitary lesion may masquerade as a pituitary adenoma. Large pituitary lesions associated with serum prolactin concentrations of less than 3000 mU/liter require early surgical biopsy.
垂体后叶肿瘤罕见，以往的命名一直令人困惑。一名40岁男性因巨大侵袭性垂体肿瘤出现视力减退和分离性高催乳素血症（830 mU/升），该肿瘤经证实为垂体细胞瘤（毛细胞型星形细胞瘤）。通过胶质纤维酸性蛋白免疫染色阳性以及电子显微镜下发现细胞质细丝，证实了其星形细胞性质。本病例报告包含垂体细胞瘤的病理描述，并表明非腺瘤性垂体病变可能伪装成垂体腺瘤。血清催乳素浓度低于3000 mU/升的大型垂体病变需要早期手术活检。
