Maiuri F, Gallicchio B, Donati P, Carandente M
Department of Neurosurgery, 2nd School of Medicine, University of Naples, Italy.
J Neurosurg Sci. 1987 Apr-Jun;31(2):45-8.
This study reviews the white blood cell count in 75 patients with subarachnoid hemorrhage and correlates it with the clinical grade at admission, the outcome, the presence of angiographic spasm and blood clots in the cisternal spaces. Patients with subarachnoid hemorrhage with normal angiograms usually have slow white cell count and favourable outcome. In patients with subarachnoid hemorrhage due to ruptured aneurysms, their'is a clear correlation between the cell count and the entity of the cisternal hemorrhage and arterial spasm. Whereas the cell count is fairly correlated with the clinical grade at admission, a cell count exceeding 20,000 in associated with a 90% rate of poor outcome, even in patients with low clinical grade at admission. Therefore the count of the white blood cells seems to have high prognostic value in predicting the neurological deterioration due to arterial spasm.
本研究回顾了75例蛛网膜下腔出血患者的白细胞计数,并将其与入院时的临床分级、预后、血管造影显示的痉挛情况以及脑池间隙内血凝块的存在情况进行关联分析。血管造影正常的蛛网膜下腔出血患者通常白细胞计数上升缓慢且预后良好。在因动脉瘤破裂导致蛛网膜下腔出血的患者中,细胞计数与脑池内出血及动脉痉挛的情况之间存在明显关联。虽然细胞计数与入院时的临床分级有一定相关性,但即使是入院时临床分级较低的患者,若细胞计数超过20,000,则预后不良率达90%。因此,白细胞计数在预测因动脉痉挛导致的神经功能恶化方面似乎具有很高的预后价值。