Wu Jianfa, Wang Sihong, Zhang Li, Wu Suqin, Liu Zhou
Department of Gynecology, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.
Department of Gynecology, Shanghai University of Medicine & Health Sciences, Shanghai, China.
Front Oncol. 2023 Jan 5;12:1028886. doi: 10.3389/fonc.2022.1028886. eCollection 2022.
Hydrometra is a common gynecological disease, especially in postmenopausal women. However, its epidemiology, harmfulness, and value in predicting gynecological tumors have not been clearly elucidated.
In this study, the prevalence rate of and risk factors for hydrometra were investigated in 3,903 women who underwent screening for gynecological diseases at Zhoupu Hospital in Shanghai from 1 January to 31 December 2021. In addition, pathological distribution of hydrometra and its predictive value in gynecological tumors were studied in another 186 patients in whom hydrometra was diagnosed sonographically at Zhoupu Hospital, from 1 January 2020 to 31 December 2021, and who underwent hysteroscopy and postoperative pathological examination.
The observed prevalence rate of hydrometra was 10.86%, which was higher than the prevalence of other gynecological diseases. Univariate and multivariate analysis indicated that advanced age (OR 1.11) and vaginitis (OR 3.18) were independent risk factors for hydrometra. Among 186 patients with a sonographic diagnosis of uterine fluid, simple hydrometra accounted for 34.41% of cases, inflammation accounted for 16.23%, and hematometra accounted for 2.15%, while gynecological tumors accounted for 5.91%. Moreover, univariate and multivariate analysis indicated that a higher body mass index (>23.92 kg/m), greater hydrometra volume (i.e., distance between the two layers of endometrium>4.75 mm), and abnormal vaginal bleeding were high-risk predictive factors for gynecological tumors.
In conclusion, hydrometra is a common disease, and is a risk factor for endometrial cancer and cervical cancer, especially in patients with higher hydrometra volume, higher BMI, and abnormal vaginal bleeding. It is necessary to pay more attention to hydrometra.
输卵管积水是一种常见的妇科疾病，在绝经后女性中尤为常见。然而，其流行病学、危害性以及在预测妇科肿瘤方面的价值尚未得到明确阐明。
在本研究中，对2021年1月1日至12月31日期间在上海周浦医院接受妇科疾病筛查的3903名女性的输卵管积水患病率及危险因素进行了调查。此外，对2020年1月1日至2021年12月31日期间在周浦医院经超声诊断为输卵管积水并接受宫腔镜检查及术后病理检查的另外186例患者，研究了输卵管积水的病理分布及其在妇科肿瘤中的预测价值。
观察到的输卵管积水患病率为10.86%，高于其他妇科疾病的患病率。单因素和多因素分析表明，高龄（OR 1.11）和阴道炎（OR 3.18）是输卵管积水的独立危险因素。在186例超声诊断为宫腔积液的患者中，单纯性输卵管积水占病例的34.41%，炎症占16.23%，积血占2.15%，而妇科肿瘤占5.91%。此外，单因素和多因素分析表明，较高的体重指数（>23.92kg/m）、较大的输卵管积水量（即子宫内膜两层之间的距离>4.75mm）和异常阴道出血是妇科肿瘤的高危预测因素。
总之，输卵管积水是一种常见疾病，是子宫内膜癌和宫颈癌的危险因素，尤其是在输卵管积水量较大、体重指数较高和有异常阴道出血的患者中。有必要更加关注输卵管积水。
