Fayyaz Hamed, Phan Thao-Ly T, Bunnell H Timothy, Beheshti Rahmatollah
University of Delaware, Newark, DE, USA.
Nemours Children's Health, Wilmington, DE, USA.
Proc Mach Learn Res. 2022 Nov;193:326-342.
Obesity is a major public health concern. Multidisciplinary pediatric weight management programs are considered standard treatment for children with obesity who are not able to be successfully managed in the primary care setting. Despite their great potential, high dropout rates (referred to as attrition) are a major hurdle in delivering successful interventions. Predicting attrition patterns can help providers reduce the alarmingly high rates of attrition (up to 80%) by engaging in earlier and more personalized interventions. Previous work has mainly focused on finding static predictors of attrition on smaller datasets and has achieved limited success in effective prediction. In this study, we have collected a five-year comprehensive dataset of 4,550 children from diverse backgrounds receiving treatment at four pediatric weight management programs in the US. We then developed a machine learning pipeline to predict (a) the likelihood of attrition, and (b) the change in body-mass index (BMI) percentile of children, at different time points after joining the weight management program. Our pipeline is greatly customized for this problem using advanced machine learning techniques to process longitudinal data, smaller-size data, and interrelated prediction tasks. The proposed method showed strong prediction performance as measured by AUROC scores (average AUROC of 0.77 for predicting attrition, and 0.78 for predicting weight outcomes).
肥胖是一个重大的公共卫生问题。多学科儿童体重管理项目被视为对在初级保健环境中无法成功管理的肥胖儿童的标准治疗方法。尽管这些项目有很大潜力,但高辍学率(称为损耗率)是提供成功干预措施的主要障碍。预测损耗模式可以帮助提供者通过开展更早且更个性化的干预措施,降低令人担忧的高损耗率(高达80%)。以往的工作主要集中在较小数据集上寻找损耗的静态预测因素,在有效预测方面取得的成功有限。在本研究中,我们收集了来自不同背景的4550名儿童在美国四个儿童体重管理项目接受治疗的五年综合数据集。然后,我们开发了一个机器学习流程,以预测(a)在加入体重管理项目后的不同时间点儿童的损耗可能性,以及(b)身体质量指数(BMI)百分位数的变化。我们的流程针对这个问题进行了大量定制,使用先进的机器学习技术来处理纵向数据、小尺寸数据和相关的预测任务。通过受试者工作特征曲线下面积(AUROC)分数衡量,所提出的方法显示出强大的预测性能(预测损耗的平均AUROC为0.77,预测体重结果的平均AUROC为0.78)。