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一例罕见的胃肿瘤:胃丛状血管黏液样纤维瘤——病例报告

An Unusual Stomach Tumour: Plexiform Angiomyxoid Fibroma Stomach-A Case Report.

作者信息

Krishnan Sharath K, Chirukandath Ravindran, Zachariah Togy, Thomas Rajiv Sajan

机构信息

Department of General Surgery, Government Medical College, Thrissur, 680596 Kerala India.

Department of Pathology, Government Medical College, Thrissur, 680596 Kerala India.

出版信息

Indian J Surg Oncol. 2022 Dec;13(4):691-695. doi: 10.1007/s13193-022-01625-4. Epub 2022 Sep 23.

Abstract

Plexiform angiomyxoid myofibroblast tumour (PAMT) is a rare mesenchymal tumour of the stomach. To date, about 45 cases of PAMT have been reported in the literature. This is an extremely rare mesenchymal gastric tumour with definite histological pattern and is a tumour typified by spindle cells with myofibroblast characteristics. A 70-year-old woman was admitted with vague upper abdominal pain and dyspepsia and on OGD was found to have a polypoidal lesion with ulceration on the posterior wall of the body of the stomach towards the greater curvature. The endoscopy biopsy suggested the above diagnosis. The patient was investigated with CT scan and CT showed a large nodular growth 10 × 8 cm with pancreatic tail involvement and splenic involvement. The patient was treated with multi-visceral resection and favourable outcome was achieved. This entity of PAMT was a histological rarity and a technically challenging case and hence was analysed and presented. PAMT is a rare mesenchymal tumour of the stomach and is characterised by spindle cells with myofibroblast characteristics with a potential to differentiate towards smooth muscle cells. These tumours have a benign course and rarely can have an infiltrative behaviour. PAMT of the stomach is a very rare mesenchymal tumour with a unique histological appearance, and it needs to be distinguished from GIST and other gastrointestinal mesenchymal tumours, although extra gastric extension and vascular invasion are sometimes observed. Here, we are reporting this case as a case of PAMT arising from the body of the stomach which required multi-visceral resection.

摘要

丛状血管黏液样肌成纤维细胞瘤(PAMT)是一种罕见的胃间叶性肿瘤。迄今为止,文献中已报道约45例PAMT。这是一种极为罕见的具有明确组织学模式的胃间叶性肿瘤,是以具有肌成纤维细胞特征的梭形细胞为典型特征的肿瘤。一名70岁女性因上腹部隐痛和消化不良入院,胃镜检查发现胃体后壁大弯侧有一个伴有溃疡的息肉样病变。内镜活检提示上述诊断。患者接受了CT扫描检查,CT显示一个10×8cm的大结节状肿物,累及胰尾和脾脏。患者接受了多脏器切除术,取得了良好的效果。PAMT这种实体在组织学上较为罕见,且在技术上具有挑战性,因此对其进行了分析并予以报道。PAMT是一种罕见的胃间叶性肿瘤,其特征为具有肌成纤维细胞特征的梭形细胞,有向平滑肌细胞分化的潜能。这些肿瘤病程良性,很少具有浸润性。胃PAMT是一种非常罕见的具有独特组织学表现的间叶性肿瘤,尽管有时会观察到胃外扩展和血管侵犯,但仍需与胃肠道间质瘤(GIST)和其他胃肠道间叶性肿瘤相鉴别。在此,我们报告这例起源于胃体且需要进行多脏器切除的PAMT病例。

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Plexiform angiomyxoid myofibroblastic tumor of the stomach: report of two cases and review of the literature.
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Plexiform angiomyxoid myofibroblastic tumor of the stomach.
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