McCargar J W, Acree W E
Department of Chemistry, Kent State University, OH 44242.
J Pharm Sci. 1987 Jul;76(7):572-4. doi: 10.1002/jps.2600760717.
Experimental solubilities are reported for anthracene and carbazole in binary dibutyl ether plus n-hexadecane and dibutyl ether plus squalane solvent mixtures at 25 degrees C. Results of these measurements, used in conjunction with the extended nearly ideal binary solvent (NIBS) model, enabled calculation of the carbazole-dibutyl ether association constant. The numerical value obtained was independent of the hydrocarbon cosolvent, and compared favorably with previously reported values based on carbazole solubilities in solvent mixtures containing much smaller alkane cosolvents.
报告了蒽和咔唑在25℃下于二丁基醚加正十六烷以及二丁基醚加角鲨烷二元混合溶剂中的实验溶解度。这些测量结果与扩展的近理想二元溶剂（NIBS）模型结合使用，能够计算咔唑与二丁基醚的缔合常数。得到的数值与烃类共溶剂无关，并且与先前基于咔唑在含有小得多的烷烃共溶剂的混合溶剂中的溶解度所报道的值相比具有优势。
