CICS-UBI-Health Sciences Research Centre, University of Beira Interior, Av. Infante D. Henrique, 6200-506 Covilhã, Portugal.
Center of Potential and Innovation of Natural Resources, Polytechnic Institute of Guarda, 6300-559 Guarda, Portugal.
Lett Appl Microbiol. 2023 Jan 23;76(1). doi: 10.1093/lambio/ovac042.
Essential oils (EOs) and their components extracted from medicinal and aromatic plants are used in several areas, such as perfumery and chemical, cosmetic, food, and pharmaceutical industries. Considering the different applications of EOs, this work aimed to screen the composition and the bioactivities properties of the EOs of Foeniculum vulgare, Helichrysum stoechas, Mentha pulegium, Pinus pinaster, Ruta graveolens, and Thymus mastichina. Gas chromatography-mass spectrometry revealed the presence of different compounds in EOs F. vulgare (12), H. stoechas (27), M. pulegium (8), P. pinaster (24), R. graveolens (8), and T. mastichina (16). All the EOs showed antioxidant activity acting through inhibition of lipid peroxidation, while only two EOs (H. stoechas and M. pulegium) scavenged the free radicals of DPPH. Mentha pulegium and T. mastichina EOs showed the strongest antimicrobial activity. Also, the effect on the fibroblast's viability was directly proportional to the EOs concentration, and the highest cytotoxic effect was registered with R. graveolens EO. The present study revealed significant bioactive properties of different EOs, highlighting M. pulegium and T. mastichina EOs to be considered in further studies for potential use in the food and pharmaceutical industries, due to their antioxidant and antimicrobial properties.
从药用和芳香植物中提取的精油 (EOs) 及其成分在香水和化工、化妆品、食品和制药等多个领域得到应用。鉴于 EOs 的不同应用，本工作旨在筛选 Foeniculum vulgare、Helichrysum stoechas、Mentha pulegium、Pinus pinaster、Ruta graveolens 和 Thymus mastichina 的 EOs 的成分和生物活性特性。气相色谱-质谱法揭示了 F. vulgare（12）、H. stoechas（27）、M. pulegium（8）、P. pinaster（24）、R. graveolens（8）和 T. mastichina（16）精油中存在不同的化合物。所有 EOs 均表现出通过抑制脂质过氧化作用的抗氧化活性，而只有两种 EOs（H. stoechas 和 M. pulegium）能清除 DPPH 的自由基。M. pulegium 和 T. mastichina EOs 表现出最强的抗菌活性。此外，对成纤维细胞活力的影响与 EOs 浓度成正比，而 R. graveolens EO 则表现出最高的细胞毒性作用。本研究揭示了不同 EOs 的显著生物活性特性，鉴于其抗氧化和抗菌特性，M. pulegium 和 T. mastichina EOs 被认为在进一步的食品和制药工业研究中具有潜在用途。
