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神经学最新进展:非典型帕金森综合征的姑息治疗概况

Neurological update: the palliative care landscape for atypical parkinsonian syndromes.

作者信息

O'Shea Noreen, Lyons Shane, Higgins Stephen, O'Dowd Sean

机构信息

Department of Neurology, Tallaght University Hospital, Tallaght, Dublin 24, D24NR0A, Ireland.

Department of Palliative Medicine, Tallaght University Hospital, Tallaght, Dublin 24, D24NR0A, Ireland.

出版信息

J Neurol. 2023 Apr;270(4):2333-2341. doi: 10.1007/s00415-023-11574-9. Epub 2023 Jan 23.

Abstract

Atypical parkinsonian syndromes are neurodegenerative conditions, characterised by rapid disease progression and shorter life expectancy compared to idiopathic Parkinson's disease. These conditions inflict substantial physical and psychosocial burden on patients and their families; hence, there is a clear rationale for a palliative care approach from diagnosis. An interdisciplinary care model has been shown to improve symptom burden, quality of life and engagement with advance care planning, in a heterogeneous group of neurodegenerative conditions. In this update, we summarise how the landscape for treating these patients has changed and the questions that still need to be resolved.

摘要

非典型帕金森综合征是神经退行性疾病,与特发性帕金森病相比,其特点是疾病进展迅速,预期寿命较短。这些疾病给患者及其家庭带来了巨大的身体和心理社会负担;因此,从诊断开始就采用姑息治疗方法有明确的理由。在一组异质性神经退行性疾病中,跨学科护理模式已被证明可以减轻症状负担、提高生活质量并促进患者参与预先护理计划。在本次更新中,我们总结了治疗这些患者的情况发生了哪些变化以及仍需解决的问题。

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