Alonso-Naranjo L, Berna-Rico E, Blanco Abbad-Jaime de Aragón C, Castañeda-Vozmediano R, Prieto-López L, Sánchez-Moya A I, Pérez-Hortet C, González-Cantero Á
Department of Dermatology, Hospital Universitario de Toledo, Toledo, Spain.
Department of Dermatology, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Actas Dermosifiliogr. 2023 Apr;114(4):299-307. doi: 10.1016/j.ad.2023.01.003. Epub 2023 Jan 20.
Teenagers' Quality of Life (T-QoL) is an age-specific measure to assess QoL of teenagers suffering from different skin diseases. A validated Spanish language version is lacking. We present the translation, cultural adaptation and validation of the T-QoL into Spanish.
A prospective study with 133 patients (between 12 and 19 years old), attended at the dermatology department of Toledo University Hospital, Spain (September 2019-May 2020), was carried out for the validation study. The International Society for Pharmacoeconomics and Outcomes Research (ISPOR) guidelines were used for the translation and cultural adaptation. We evaluated the convergent validity with the Dermatology Life Quality Index (DLQI), the Children's Dermatology Life Quality Index (CDLQI) and with a Global Question (GQ) on self-assessed disease severity. We also analysed internal consistency and reliability of the T-QoL tool and confirmed its structure with a factor analysis.
Global T-QoL scores significantly correlated with the DLQI and the CDLQI (r=0.75) and with the GQ (r=0.63). The confirmatory factor analysis showed optimal fit for the bi-factor model and an adequate fit for the correlated three-factor model. Reliability indicators were high (Cronbach's α=0.89; Guttman's Lambda 6 index=0.91; Omega ω=0.91) and test-retest showed a high stability (ICC=0.85). The results were consistent with those found by the authors of the original test.
Our Spanish version of the T-QoL tool is valid and reliable to assess QoL of Spanish-speaking adolescents with skin diseases.
青少年生活质量（T-QoL）是一种针对特定年龄段的测量工具，用于评估患有不同皮肤病的青少年的生活质量。目前缺乏经过验证的西班牙语版本。我们展示了T-QoL翻译成西班牙语、文化适应性调整及验证的过程。
在西班牙托莱多大学医院皮肤科（2019年9月至2020年5月）对133名患者（年龄在12至19岁之间）进行了一项前瞻性研究，以进行验证研究。翻译和文化适应性调整采用了国际药物经济学和结果研究协会（ISPOR）的指南。我们通过皮肤病生活质量指数（DLQI）、儿童皮肤病生活质量指数（CDLQI）以及关于自我评估疾病严重程度的总体问题（GQ）来评估收敛效度。我们还分析了T-QoL工具的内部一致性和可靠性，并通过因子分析确认了其结构。
T-QoL总体得分与DLQI、CDLQI（r = 0.75）以及GQ（r = 0.63）显著相关。验证性因子分析显示双因子模型拟合优度最佳，相关三因子模型拟合度良好。可靠性指标较高（Cronbach's α = 0.89；Guttman's Lambda 6指数 = 0.91；Omega ω = 0.91），重测显示稳定性较高（ICC = 0.85）。结果与原始测试作者的发现一致。
我们的西班牙语版T-QoL工具对于评估患有皮肤病的西班牙语青少年的生活质量是有效且可靠的。
