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奥洛夫·奥斯卡森(1931-1996),来自隆德大学,小脑神经生物学的先驱。

Olov Oscarsson (1931-1996) of Lund University, a Pioneer in Cerebellar Neurobiology.

机构信息

Department of Psychology, Sector of Cognitive, Behavioral and Brain Sciences, Faculty of Philosophy, Aristotelian University, University Campus, Thessaloniki, 54124, Greece.

Unité Des Ataxies Cérébelleuses, CHU-Charleroi, Charleroi, Belgium.

出版信息

Cerebellum. 2024 Apr;23(2):279-283. doi: 10.1007/s12311-023-01515-7.

DOI:10.1007/s12311-023-01515-7
PMID:36690830
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10951007/
Abstract

The present Cerebellar Classic highlights the experimental work of the Swedish neurophysiologist Olov Oscarsson (1931-1996) on the afferent innervation of the cerebellum by axons emanating from neurons in the spinal cord and the inferior olive. Historically, the schemes of cerebellar division had been principally based on the external morphology of lobules and fissures. However, the macroscopic anatomical division of the cerebellum does not coincide with its pattern of functional organization. By defining a system of longitudinal somatotopy, Oscarsson contributed to the much needed plan of cerebellar division that correlates experimental information on axonal connections with physiology. His contribution has ultimately led to the currently accepted microzonal modular scheme of cerebellar corticonuclear microcomplexes.

摘要

本小脑经典聚焦于瑞典神经生理学家 Olov Oscarsson(1931-1996 年)的实验工作,他研究了脊髓和下橄榄核神经元发出的轴突对小脑的传入神经支配。从历史上看,小脑的划分方案主要基于小叶和裂的外部形态。然而,小脑的宏观解剖划分与它的功能组织模式并不吻合。通过定义一个纵向体节系统,Oscarsson 为小脑的划分做出了急需的贡献,将轴突连接的实验信息与生理学联系起来。他的贡献最终导致了目前被广泛接受的小脑皮质核微复合体的微区模块方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b16/10951007/231528acc027/12311_2023_1515_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b16/10951007/231528acc027/12311_2023_1515_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b16/10951007/231528acc027/12311_2023_1515_Fig1_HTML.jpg

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本文引用的文献

1
Olov Oscarsson's Description of Afferent Pathways to the Cerebellum: Excellent Physiology, Base for Anatomy, and Road Toward Understanding Function.奥洛夫·奥斯卡森对小脑传入途径的描述:优秀的生理学基础,解剖学基础,以及通往理解功能之路。
Cerebellum. 2024 Apr;23(2):284-328. doi: 10.1007/s12311-023-01516-6.
2
Cerebellar zones: a personal history.小脑分区:个人史。
Cerebellum. 2011 Sep;10(3):334-50. doi: 10.1007/s12311-010-0221-6.
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Anatomical and physiological foundations of cerebellar information processing.小脑信息处理的解剖学和生理学基础。
Nat Rev Neurosci. 2005 Apr;6(4):297-311. doi: 10.1038/nrn1646.
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Functional organization of the ventral spino-cerebellar tract in the cat. IV. Identification of units by antidromic activation from the cerebellar cortex.猫腹侧脊髓小脑束的功能组织。IV. 通过小脑皮质的逆向激活鉴定神经元单位。
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FUNCTIONAL ORGANIZATION OF THE SPINO- AND CUNEOCEREBELLAR TRACTS.脊髓小脑束和楔小脑束的功能组织
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IDENTIFICATION OF A SPINOCEREBELLAR TRACT ACTIVATED FROM FORELIMB AFFERENTS IN THE CAT.猫前肢传入激活的脊髓小脑束的鉴定
Acta Physiol Scand. 1964 Sep-Oct;62:125-36. doi: 10.1111/j.1748-1716.1964.tb03960.x.
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THREE ASCENDING TRACTS ACTIVATED FROM GROUP I AFFERENTS IN FORELIMB NERVES OF THE CAT.
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Functional organization of the cuneocrebellar tract in the cat.猫楔小脑束的功能组织
Acta Physiol Scand. 1963 Jun-Jul;58:216-35. doi: 10.1111/j.1748-1716.1963.tb02643.x.
9
Synaptic action of group I and II afferent fibres of muscle on the cells of the dorsal spinocerebellar tract.肌肉的I类和II类传入纤维对脊髓背小脑束细胞的突触作用。
J Physiol. 1961 Oct;158(3):517-43. doi: 10.1113/jphysiol.1961.sp006783.
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Intracellular recording from cells of the ventral spinocerebellar tract.从腹侧脊髓小脑束细胞进行细胞内记录。
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