Division of Neurosurgery, Ascension Providence Hospital, Michigan State University, College of Human Medicine, Southfield, Michigan, USA
Division of Neurosurgery, Ascension Providence Hospital, Michigan State University, College of Human Medicine, Southfield, Michigan, USA.
BMJ Open. 2022 Sep 6;12(9):e056989. doi: 10.1136/bmjopen-2021-056989.
INTRODUCTION: Sacroiliac joint (SIJ) dysfunction has been shown to cause significant morbidity. Current treatment includes conservative management and surgical intervention. Previously published data reporting clinical and surgical outcomes reached conflicting conclusions. This protocol aims to conduct a meta-analysis to determine fusion rates and patient-reported outcomes of minimally invasive (MIS) SIJ fusions compared with conservative treatment. METHODS AND ANALYSIS: We drafted our protocol according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols guidelines. We will search PubMed, Embase and the Cochrane Library, supplemented by manual search when necessary. Two independent reviewers will screen for eligibility by title/abstract, then full text, arbitrated by a third reviewer if necessary. The two reviewers will carry out a risk of bias assessment using the Cochrane Collaboration Risk of Bias tool for randomised controlled trial and the Methodological Index for Non-Randomised Studies tool for observational cohort studies. A third reviewer will arbitrate any disagreement. We will perform data synthesis using Review Manager (RevMan for Windows, V.5.4.1, The Cochrane Collaboration, 2020) and Comprehensive Meta-Analysis (V.3.3.070). Meta-bias will be evaluated and confidence determined using the Grading of Recommendations, Assessment, Development and Evaluation guidelines. ETHICS AND DISSEMINATION: Ethical approval for this review will not be required as no patient data is being collected. The results of this study will be submitted for publication in peer-reviewed journals. PROSPERO REGISTRATION NUMBER: CRD42021273481.
简介:骶髂关节(SIJ)功能障碍已被证明会导致显著的发病率。目前的治疗包括保守治疗和手术干预。先前发表的数据报告了临床和手术结果,得出了相互矛盾的结论。本方案旨在进行荟萃分析,以确定微创(MIS)SIJ 融合与保守治疗相比的融合率和患者报告的结果。
方法和分析:我们根据系统评价和荟萃分析方案的首选报告项目起草了我们的方案。我们将搜索 PubMed、Embase 和 Cochrane 图书馆,并在必要时补充手动搜索。两名独立评审员将通过标题/摘要筛选合格性,然后是全文,如有必要,由第三名评审员仲裁。两名评审员将使用 Cochrane 协作风险偏倚工具对随机对照试验和非随机研究方法学指数对观察性队列研究进行风险偏倚评估。任何分歧将由第三名评审员仲裁。我们将使用 Review Manager(RevMan for Windows,V.5.4.1,Cochrane 协作,2020)和 Comprehensive Meta-Analysis(V.3.3.070)进行数据综合。使用推荐分级、评估、发展和评估指南评估元偏倚并确定置信度。
伦理和传播:由于不收集患者数据,因此本次审查不需要伦理批准。本研究的结果将提交给同行评议期刊发表。
PROSPERO 注册号:CRD42021273481。
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