Lee M G, Hanchard B, Donaldson E K, Charles C, Hall J S
Department of Medicine, University Hospital, Kingston, Jamaica.
J Trop Med Hyg. 1987 Oct;90(5):245-8.
Pregnancy in chronic active hepatitis and cirrhosis is rare. There is an appreciable perinatal mortality and the effect of pregnancy on the underlying liver disease remains uncertain. Two patients with autoimmune chronic active hepatitis with cirrhosis who became pregnant during an active stage of their disease while on therapy are described. Both had an uneventful pregnancy with successful deliveries. One of the patients had two other pregnancies but the pregnancy had to be terminated because of clinical deterioration. With close supervision patients with chronic active hepatitis and cirrhosis may have successful pregnancies.
慢性活动性肝炎和肝硬化患者怀孕的情况较为罕见。围产期死亡率较高，且怀孕对基础肝病的影响尚不确定。本文描述了两名自身免疫性慢性活动性肝炎合并肝硬化的患者，她们在疾病活动期接受治疗时怀孕。两人均顺利度过孕期并成功分娩。其中一名患者还有另外两次怀孕经历，但因病情恶化不得不终止妊娠。在密切监测下，慢性活动性肝炎和肝硬化患者可能成功怀孕。
