Hillmann Henrike A K, Betz Konstanze, Linz Dominik, Duncker David
Hannover Herzrhythmus Centrum, Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Department of Cardiology and Cardiovascular Research Institute Maastricht (CARIM), Maastricht University Medical Centre, Maastricht, Niederlande.
Herzschrittmacherther Elektrophysiol. 2023 Mar;34(1):82-90. doi: 10.1007/s00399-022-00919-y. Epub 2023 Jan 24.
Antiarrhythmic drugs are important for the noninvasive rhythm control therapy of heart rhythm disorders. Antiarrhythmic drugs, which can be categorized into subgroups based on their different effects on ion channels, are clinically used for various types of arrhythmias. Knowledge about these specific electrophysiological effects contributes to a better understanding in order to select the correct drug for each specific arrhythmia. This review summarizes mechanisms, indications, contraindications, and side effects of the different antiarrhythmic drugs and, thus, supports their adequate use in daily clinical routine.
抗心律失常药物对于心律失常的非侵入性节律控制治疗至关重要。抗心律失常药物可根据其对离子通道的不同作用分为不同亚组，临床上用于治疗各种类型的心律失常。了解这些特定的电生理效应有助于更好地理解，以便为每种特定的心律失常选择正确的药物。本综述总结了不同抗心律失常药物的作用机制、适应证、禁忌证和副作用，从而支持它们在日常临床实践中的合理使用。
